6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m catalyzes the transfer of AMP from the E-AMP complex to diverse compounds, generating the product indicated between parentheses, ATP(Ap4A), NTP (Ap4N), P3 or P4 (p4A or p5A), ADP (Ap3A) Tequatrovirus T4 AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m participates in repair, splicing and editing pathways, reseals broken RNAs or alters their primary structure, catalyzes intramolecular and intermolecular RNA strand joining through ligase-adenylate and RNA adenylate intermediates Tequatrovirus T4 AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m RNA editing, essential for proliferation of Trypanosoma brucei Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m RNA editing, posttranscriptional insertion and deletion of uridylate residues in mitochondrial transcripts Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m RNA editing, posttranscriptional process by which uridine residues are added and deleted from mitochondrial mRNAs Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m RNA editing, posttranscriptional RNA processing in which uridylate residues are inserted into and deleted from pre-mRNAs to create start and stop codons, also acts to reseal mRNAs cleaved at incorrect sites Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m RNA editing, unique U insertion and U deletion process, involves cycles of pre-mRNA cleavage, terminal U addition or U removal, and religation, band IV is the RNA editing ligase needed to seal in U deletion Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m RNA-editing Tequatrovirus T4 AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m the enzyme is essential for survival of both insect and bloodstream forms of the parasite Trypanosoma brucei AMP + diphosphate + (ribonucleotide)n+m - ? 813 6.5.1.3 ATP + (ribonucleotide)n + (ribonucleotide)m DraRnl seals 3'-OH/5'-PO4 RNA nicks in either a duplex RNA or an RNA:DNA hybrid, but it cannot seal 3'-OH/5'-PO4 DNA nicks Deinococcus radiodurans AMP + diphosphate + (ribonucleotide)n+m - ? 813