3.4.22.64 additional information dimerised caspase-11 cannot cleave pro-interleukin-1beta of either species, mouse or human ? - - 89 3.4.22.64 additional information mouse caspase-11 cannot cleave IL-1beta efficiently ? - - 89 3.4.22.64 additional information mouse caspase-11 has an inadequate capacity to cleave pro-IL-1beta. It cleaves gasdermin D more efficiently than pro-IL-1beta ? - - 89 3.4.22.64 mouse interleukin-18 + H2O low activity ? - ? 465330 3.4.22.64 Pro-interleukin-1beta + H2O - ? - ? 432907 3.4.22.64 procaspase-1 + H2O the enzyme is an upstream activator of caspase-1 ? - ? 362372 3.4.22.64 procaspase-1 + H2O - ? - ? 362372 3.4.22.64 procaspase-3 + H2O - ? - ? 362371 3.4.22.64 procaspase-3 + H2O the enzyme is a critical initiator caspase responsible for the activation of caspase-3 ? - ? 362371