3.4.21.7 ADAMTS13 + H2O inactivation Homo sapiens ? - ? 384122 3.4.21.7 AIYRSR + H2O - Homo sapiens AIYR + Ser-Arg - ? 365826 3.4.21.7 alpha-lactalbumin + H2O hydrolysis is highly dependent on photooxidation state of substrate Bos taurus ? - ? 366257 3.4.21.7 alphaS-casein + H2O hydrolysis is highly dependent on photooxidation state of substrate Bos taurus ? - ? 384172 3.4.21.7 alphas1-casein + H2O - Bos taurus ? - ? 396403 3.4.21.7 amyloid beta peptide Abeta42 + H2O cleavage prevents the aggregation of Abeta42 and its cleavage products into beta-pleated sheet structure Homo sapiens ? - ? 365803 3.4.21.7 amyloid-beta + H2O plasmin cleaves at multiple sites Homo sapiens ? - ? 365809 3.4.21.7 amyloid-beta + H2O the plasmin pathway is induced by aggregated amyloid-beta, which can lead to amyloid-beta degradation and inhibition of amyloid-beta actions Homo sapiens ? - ? 365809 3.4.21.7 annexin A2 + H2O interaction of plasmin with annexin A2 results in the stimulation of ERK1/2 and p38 MAPK, cyclooxygenase-2, and PGE(2), leading to increased matrix metalloproteinase-1 production Homo sapiens ? - ? 391292 3.4.21.7 annexin A2 + H2O stimulation of macrophages with plasmin leads to cleavage of ca. 6% of annexin A2 yielding a proteolytic fragment of ca. 33 kDa Homo sapiens ? - ? 391292