2.7.11.10 additional information interaction analysis of IKKepsilon with NF-kappaB complex components/p25/p65 by immunoprecipitation and mass spectrometric analysis, overview Mus musculus ? - ? 89 2.7.11.10 additional information the enzyme activity is included in a complex formed of the scaffold protein NF-kappaB essential modulator, i.e. NEMO or IKKgamma, and the Ikkalpha and IKKbeta kinases, overview Mus musculus ? - ? 89 2.7.11.10 additional information IKKalpha and IKKbeta are distinctly involved in ERK1-dependent, but IkappaBalpha-P65- and p100-p52-independent, upregulation of MUC5AC mucin transcription in case of infection by Streptococcus pneumoniae, MUC5AC mucin induction also requires pneumolysin and TLR4-dependent MyD88-IRAK1-TRAF6 signaling, molecular mechanism, overview Mus musculus BALB/c ? - ? 89 2.7.11.10 additional information activation of NFkappaB by the catalytic subunit IKKbeta is required for signaling via the NFkappaB pathway in acute and systemic inflammation and for tissue protection Mus musculus C57/BL6J ? - ? 89 2.7.11.10 ATP + a protein autophosphorylation at both Ser and Thr Myxococcus xanthus ADP + a phosphoprotein - ? 323385 2.7.11.10 ATP + a protein the expression of pkn1 is developmentally regulated to start immediately before spore formation. The enzyme plays an important role in the onset of proper differentiation Myxococcus xanthus ADP + a phosphoprotein - ? 323385 2.7.11.10 ATP + IkappaBalpha - Rattus norvegicus ADP + phosphorylated-IkappaBalpha - ? 400184 2.7.11.10 ATP + [IkappaB protein] - Rattus norvegicus ADP + [IkappaB phosphoprotein] - ? 378623 2.7.11.10 ATP + [MYPT1] the enzyme phosphorylates MYPT1 at Thr853 Rattus norvegicus ADP + [MYPT1 phosphoprotein] - ? 458579 2.7.11.10 additional information the IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories, IKKalpha is involved in the regulation of histone H3 phosphorylation and acetylation at specific gene promoters in hippocampus in the NF-kappaB pathway, inhibition of IKKalpha regulation results in impairments in fear memory reconsolidation, mechanism, overview Rattus norvegicus ? - ? 89