2.7.11.10	additional information	no activity with Rip2	Homo sapiens	?	-	?	89	
2.7.11.10	additional information	the enzyme activity is included in a complex formed of the scaffold protein NF-kappaB essential modulator, i.e. NEMO or IKKgamma, and the Ikkalpha and IKKbeta kinases, overview	Mus musculus	?	-	?	89	
2.7.11.10	additional information	activation of NFkappaB by the catalytic subunit IKKbeta is required for signaling via the NFkappaB pathway in acute and systemic inflammation and for tissue protection	Mus musculus C57/BL6J	?	-	?	89	
2.7.11.10	additional information	IKKalpha and IKKbeta are distinctly involved in ERK1-dependent, but IkappaBalpha-P65- and p100-p52-independent, upregulation of MUC5AC mucin transcription in case of infection by Streptococcus pneumoniae, MUC5AC mucin induction also requires pneumolysin and TLR4-dependent MyD88-IRAK1-TRAF6 signaling, molecular mechanism, overview	Mus musculus BALB/c	?	-	?	89