1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ the enzyme catalyses the second reaction in the diaminopimelate pathway of lysine biosynthesis in bacteria and plants Arabidopsis thaliana (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ the enzyme catalyses the second reaction in the diaminopimelate pathway of lysine biosynthesis in bacteria and plants Vitis vinifera (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ the enzyme catalyzes the second committed step in the diaminopimelate/lysine anabolic pathways Bartonella henselae (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ the enzyme is involved in L-lysine biosynthesis Corynebacterium glutamicum (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ it is proposed that the the domain movement for active site constitution occurs when both cofactor and substrate bind to the enzyme Corynebacterium glutamicum (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ the enzyme is involved in L-lysine biosynthesis Corynebacterium glutamicum ATCC 13032 (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ it is proposed that the the domain movement for active site constitution occurs when both cofactor and substrate bind to the enzyme Corynebacterium glutamicum ATCC 13032 (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ the enzyme catalyzes the second committed step in the diaminopimelate/lysine anabolic pathways Bartonella henselae Houston 1 (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O - ? 442107 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+ - Staphylococcus aureus (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD+ + H2O - ir 422175 1.17.1.8 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NADH + H+ - Pseudomonas aeruginosa (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD+ + H2O - ir 422175