1.14.13.83	precorrin-3A + NADH + H+ + O2	the Brucella melitensis enzyme is fully active in vitro (20 mM Tris-HCl buffer, pH 8.0, with 100 mM NaCl, S-adenosyl-L-methionine (SAM), 5-aminolevulinic acid (ALA) and NADPH, aerobic, dark, 4°C) and the mononuclear non-heme iron is reducible by dithionite and then is able to react with NO as oxygen analogue in the presence of the substrate	Brucella melitensis 16M	precorrin-3B + NAD+ + H2O	-	?	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	-	Pseudomonas denitrificans (nom. rej.) SC510 (RifT)	precorrin-3B + NAD+ + H2O	-	ir	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	pathway to coenzyme B12, biosynthesis of the corrin macrocycle, catalyzes a complex oxidative reaction involving C20 hydroxylation and gamma-lactone formation from ring-A acetate to C1	Pseudomonas denitrificans (nom. rej.) SC510 (RifT)	precorrin-3B + NAD+ + H2O	-	ir	363718	
1.14.13.83	precorrin-3A + NADH + O2	-	Pseudomonas denitrificans (nom. rej.)	precorrin-3B + NAD+ + H2O	-	?	359083	
1.14.13.83	precorrin-3A + NADH + O2	the enzyme is involved in ring contraction, whereby an integral carbon atom of the tetrapyrrole-derived macrocycle is removed, and cobalt chelation during aerobic synthesis of vitamin B12, the catalytic cycle of CobZ, overview	Rhodobacter capsulatus	precorrin-3B + NAD+ + H2O	-	?	359083	
1.14.13.83	precorrin-3A + NADH + O2	the enzyme generates a hydroxy lactone intermediate	Rhodobacter capsulatus	precorrin-3B + NAD+ + H2O	-	?	359083	
1.14.13.83	precorrin-3A + NADH + O2	-	Pseudomonas denitrificans (nom. rej.) SC510 (RifT)	precorrin-3B + NAD+ + H2O	-	?	359083	
1.14.13.83	precorrin-3A + NADH + H+ + O2	-	Pseudomonas denitrificans (nom. rej.)	precorrin-3B + NAD+ + H2O	aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4	ir	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	biosynthesis of vitamin B12	Pseudomonas denitrificans (nom. rej.)	precorrin-3B + NAD+ + H2O	aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4	ir	363718	
1.14.13.83	precorrin-3A + NADH + H+ + O2	-	Pseudomonas denitrificans (nom. rej.) G3575	precorrin-3B + NAD+ + H2O	aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4	ir	363718