7.2.2.9 aorta - 668543 7.2.2.9 ARPE-19 cell - 669011 7.2.2.9 astrocyte - 670415 7.2.2.9 BHY cell - 697073 7.2.2.9 bile canaliculus cellular distribution of ATP7B, stable ATP7B pool localized to the tight junctions that seal the bile canaliculi shown 686925 7.2.2.9 bile duct ATP7B is expressed in bile duct epithelial cells, where it may mediate copper secretion into bile fluid 667210 7.2.2.9 brain - 246908, 246909 7.2.2.9 brain ATP7A expression is most abundant in the early postnatal period, reaching peak levels at P4 in neocortex and cerebellum. In the developing and adult brain, ATP7A levels are greatest in the choroid plexus/ependymal cells of the lateral and third ventricles. ATP7A expression decreases in most neuronal subpopulations from birth to adulthood. ATP7A expression increases in CA2 hippocampal pyramidal and cerebellar Purkinje neurons 670415 7.2.2.9 brain ATP7A is widely expressed throughout the CNS 712175 7.2.2.9 brain expression of ATP7A, not of ATP7B 713537