1.1.1.146 11beta-hydroxysteroid dehydrogenase macrophage activity occurs after differentiation of neutrophils to macrophages 669730 1.1.1.146 11beta-hydroxysteroid dehydrogenase macrophage derived from bone-marrow, peritoneal macrophages, expression of isozyme 11beta-HSD1, not isozyme 11beta-HSD2 669730 1.1.1.146 11beta-hydroxysteroid dehydrogenase macrophage isoform 11betaHSD2 741066 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) macrophage - 286017 1.1.1.188 prostaglandin-F synthase macrophage peritoneal 654851 1.1.1.21 aldose reductase macrophage - -, 669503, 738833, 739113 1.1.1.21 aldose reductase macrophage in inflamed temporal arteries 668868 1.1.1.271 GDP-L-fucose synthase macrophage - 667231 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+) macrophage - 655495 1.11.2.2 myeloperoxidase macrophage - 697307, 700458 1.13.11.11 tryptophan 2,3-dioxygenase macrophage - 743358 1.13.11.31 arachidonate 12-lipoxygenase macrophage - -, 704947, 726846, 741573 1.13.11.31 arachidonate 12-lipoxygenase macrophage 12/15-LOX is a macrophage-selective regulator of interleukin-12 production -, 704003 1.13.11.31 arachidonate 12-lipoxygenase macrophage 12/15-LOX is expressed by 95% of resident peritoneal CD11bhigh cells, with the remaining 5% being 12/15-LOX-. 12/15-LOX+ cells are phenotypically defined by high F4/80, SR-A, and Siglec1 expression, and enhanced IL-10 and G-CSF generation. In contrast, 12/15-LOX- cells are a dendritic cell population. Resident peritoneal macrophage numbers are significantly increased in 12/15-LOX-/- mice, suggesting alterations in migratory trafficking or cell differentiation in vivo -, 704943 1.13.11.31 arachidonate 12-lipoxygenase macrophage macrophages that overexpress 12/15LO have reduced ATP-binding cassette G1 expression, increased transporter phosphorylation, and reduced cholesterol efflux 704567 1.13.11.31 arachidonate 12-lipoxygenase macrophage peritoneal -, 684803 1.13.11.31 arachidonate 12-lipoxygenase macrophage resident peritoneal 742000 1.13.11.33 arachidonate 15-lipoxygenase macrophage - 703628, 742239 1.13.11.33 arachidonate 15-lipoxygenase macrophage 12/15-LOX is a macrophage-selective regulator of interleukin-12 production -, 704003 1.13.11.33 arachidonate 15-lipoxygenase macrophage 12/15-LOX is expressed by 95% of resident peritoneal CD11bhigh cells, with the remaining 5% being 12/15-LOX-. 12/15-LOX+ cells are phenotypically defined by high F4/80, SR-A, and Siglec1 expression, and enhanced IL-10 and G-CSF generation. In contrast, 12/15-LOX- cells are a dendritic cell population. Resident peritoneal macrophage numbers are significantly increased in 12/15-LOX-/- mice, suggesting alterations in migratory trafficking or cell differentiation in vivo -, 704943 1.13.11.33 arachidonate 15-lipoxygenase macrophage alveolar 742613 1.13.11.33 arachidonate 15-lipoxygenase macrophage high level expression in peritoneal macrophages, while murine peripheral monocytes, alveolar macrophages and bone marrow-derived macrophages express alox15 only at low levels 742613 1.13.11.33 arachidonate 15-lipoxygenase macrophage isozyme 15-LO-1, differentiated monocytes obtained from human venous blood, CD14+ 687235 1.13.11.33 arachidonate 15-lipoxygenase macrophage peritoneal -, 684350 1.13.11.33 arachidonate 15-lipoxygenase macrophage resident peritoneal 742000 1.13.11.33 arachidonate 15-lipoxygenase macrophage rheumatoid arthritis tissue 701978 1.13.11.34 arachidonate 5-lipoxygenase macrophage - 660111, 704997, 711100, 713540, 743614 1.13.11.34 arachidonate 5-lipoxygenase macrophage alveolar macrophage 742001 1.13.11.52 indoleamine 2,3-dioxygenase macrophage - 666461, 711952, 743358 1.13.11.52 indoleamine 2,3-dioxygenase macrophage enzyme is induced in monocyte-derived macrophages treated with human recombinant interferon-beta or interferon gamma 395468 1.13.11.52 indoleamine 2,3-dioxygenase macrophage in the villous stroma and in the fetal membrane 659803 1.14.11.29 hypoxia-inducible factor-proline dioxygenase macrophage - 745510 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase macrophage expressed in macrophages in response to bacterial products and inflammatory cytokines 753165 1.14.13.39 nitric-oxide synthase (NADPH) macrophage - -, 440193, 440195, 440198, 440204, 440206, 440207, 440208, 440209, 440219, 440226, 440234, 440236, 674558 1.14.13.39 nitric-oxide synthase (NADPH) macrophage alveolar 690183 1.14.13.39 nitric-oxide synthase (NADPH) macrophage bone marrow-derived 687727 1.14.13.39 nitric-oxide synthase (NADPH) macrophage Ca2+-independent form 440200, 440201 1.14.13.39 nitric-oxide synthase (NADPH) macrophage cytokine-activated 440192, 440200, 440219 1.14.13.39 nitric-oxide synthase (NADPH) macrophage in liver, lung, kidney, isoform II 440226 1.14.13.39 nitric-oxide synthase (NADPH) macrophage inducible enzyme 671728 1.14.13.39 nitric-oxide synthase (NADPH) macrophage iNOS 687358 1.14.13.39 nitric-oxide synthase (NADPH) macrophage iNOS is the predominant isozyme in macrophages 695853 1.14.13.39 nitric-oxide synthase (NADPH) macrophage NOS2 701646 1.14.13.39 nitric-oxide synthase (NADPH) macrophage RAW 264.7 cells 440219, 440221, 440222, 440223, 440225, 440236, 440238 1.14.13.9 kynurenine 3-monooxygenase macrophage - 763915, 764034 1.14.13.9 kynurenine 3-monooxygenase macrophage in first and second trimester of the placenta, within the fetal villus 660112 1.14.14.18 heme oxygenase (biliverdin-producing) macrophage - 684920, 685498, 686078, 688061, 688881, 705614, 733904 1.14.14.18 heme oxygenase (biliverdin-producing) macrophage peritoneal, alveolar 438244 1.14.14.29 25/26-hydroxycholesterol 7alpha-hydroxylase macrophage bone marrow-derived 699414 1.14.15.15 cholestanetriol 26-monooxygenase macrophage - 703582 1.14.15.18 calcidiol 1-monooxygenase macrophage - 675057, 675686 1.14.15.18 calcidiol 1-monooxygenase macrophage expression of 1alpha-hydroxylase is intimately associated with toll-like receptor, TLR, recognition of pathogens in macrophages 712885 1.14.15.18 calcidiol 1-monooxygenase macrophage monocyte-derived 688675 1.14.16.5 alkylglycerol monooxygenase macrophage - 746303 1.14.99.38 cholesterol 25-monooxygenase macrophage - -, 699414, 700999, 715833, 744738 1.14.99.38 cholesterol 25-monooxygenase macrophage testicular 658244, 658246 1.14.99.38 cholesterol 25-monooxygenase macrophage testicular, 10-day-old animals have the highest steady-state levels of message 658245 1.15.1.1 superoxide dismutase macrophage - 685864 1.15.1.1 superoxide dismutase macrophage peritoneal macrophages exposed to He-Ne laser radiation. Changes in the activity of superoxide dismutase as well as the formation of nitric oxide and peroxynitrite depend to a large extent on the laser radiation dose. Activation of enzyme at low radiation doses is accompanied by nitric oxide level increase without changes in peroxynitrite. Enhanced laser radiation doses inhibit the enzyme 672292 1.16.3.1 ferroxidase macrophage - 438021 1.17.3.2 xanthine oxidase macrophage alveolar macrophages purified from the lung by lavage, and interstitial macrophages. Inflammatory cells express high levels of XOR activity, while in resident alveolar macrophage the enzyme content is extremely low prior to cytokine insufflation -, 715663 1.2.1.104 pyruvate dehydrogenase system macrophage - 763502 1.2.1.13 glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) macrophage peritoneal 288005 1.2.1.36 retinal dehydrogenase macrophage hepatic 743375 1.2.4.1 pyruvate dehydrogenase (acetyl-transferring) macrophage - 763502 1.3.1.21 7-dehydrocholesterol reductase macrophage - 763129 1.3.1.24 biliverdin reductase macrophage - 673797, 698922, 740486, 740549 1.3.1.24 biliverdin reductase macrophage increased expression in macrophages of primary spontaneous pneumothorax of smokers compared to non-smokers 713359 1.3.1.24 biliverdin reductase macrophage lung 713359 1.4.3.2 L-amino-acid oxidase macrophage - 726320 1.4.3.2 L-amino-acid oxidase macrophage immunostaining in macrophages associated with non small-cell lung carcinomas, mesotheliomas, colorectal carcinomas and testicular germ cell tumors, positive staining in germinal centers of reactive lymph nodes and hyperplastic tonsils, and in the spleen 699933 1.5.3.16 spermine oxidase macrophage - 725128, 741582 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific) macrophage bone marrow-derived, Nnt mRNA and protein are expressed in resting macrophages and down-regulated in response to inflammatory stimuli such as lipopolysaccharide. Nnt mRNA and protein expression are further repressed in fully activated macrophages 724953 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific) macrophage bone marrow-derived, Nnt mRNA and protein are expressed in resting macrophages and down-regulated in response to inflammatory stimuli such as lipopolysaccharide. Nnt mRNA and protein expression are repressed in fully activated macrophages 724953 1.6.3.1 NAD(P)H oxidase (H2O2-forming) macrophage - 742310, 743287 1.6.3.1 NAD(P)H oxidase (H2O2-forming) macrophage alveolar macrophages. Inhibition of NAD(P)H oxidase by apocynin results in down-regulation of arginase 686562 1.6.3.1 NAD(P)H oxidase (H2O2-forming) macrophage Burkholderia cenocepacia resides in macrophage vacuoles displaying an altered recruitment of the NADPH oxidase complex at the phagosomal membrane 700052 1.6.3.1 NAD(P)H oxidase (H2O2-forming) macrophage isoforms NOX2 and NOX4 742567 1.6.5.2 NAD(P)H dehydrogenase (quinone) macrophage enzyme is highly upregulated in active and chronic multiple sclerosis lesions, particularly in hypertrophic astrocytes and myelin-laden macrophages 673798 1.8.1.7 glutathione-disulfide reductase macrophage - 690144 1.8.4.12 peptide-methionine (R)-S-oxide reductase macrophage highly expressed in immune-activated macrophages 765804 1.8.4.2 protein-disulfide reductase (glutathione) macrophage - 394863 2.1.1.319 type I protein arginine methyltransferase macrophage - 756732 2.1.1.355 [histone H3]-lysine9 N-trimethyltransferase macrophage - 755432 2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase macrophage - 753191 2.1.1.364 [histone H3]-lysine4 N-methyltransferase macrophage - 704436 2.1.1.366 [histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase macrophage - 755432 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase macrophage - 701644 2.2.1.1 transketolase macrophage at the lesion border 694176 2.3.1.147 glycerophospholipid arachidonoyl-transferase (CoA-independent) macrophage - 16268 2.3.1.148 glycerophospholipid acyltransferase (CoA-dependent) macrophage - 16278 2.3.1.15 glycerol-3-phosphate 1-O-acyltransferase macrophage bone marrow-derived macrophages -, 756014 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase macrophage - 704461, 736546, 756102 2.3.1.23 1-acylglycerophosphocholine O-acyltransferase macrophage primary peripheral blood macrophages 735571 2.3.1.26 sterol O-acyltransferase macrophage - 486696, 486703, 684800, 702552, 702650, 703975, 736792 2.3.1.26 sterol O-acyltransferase macrophage ACAT1, villus 486708 2.3.1.26 sterol O-acyltransferase macrophage loss of ACAT activity in macrophages, either by pharmacological inhibition or by genetic knockout of ACAT-1, results in reduced induction of apoptosis in response to 7-ketocholesterol or oxidized low density lipoproteins. The apoptotic signal generated in macrophages by ACAT may be an arachidonyl oxysterol 675261 2.3.1.26 sterol O-acyltransferase macrophage monocyte-derived macrophage 684780 2.3.1.26 sterol O-acyltransferase macrophage relative high level of mRNA 486703 2.3.1.48 histone acetyltransferase macrophage - -, 702855