5.3.99.3 prostaglandin-E synthase follicular dendritic cell line - 693452 5.3.99.4 prostaglandin-I synthase follicular dendritic cell line constitutive expression of prostaglandin-I synthase and cyclooxygenase-1 in HK cells, while expression of cyclooxygenase-2 and prostaglandin-E synthase are up-regulated in response to tumor necrosis factor-alpha, tumor growth factor-beta, and lipopolysaccharide 693452