1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) breast cancer cell - 700197 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD+) breast cancer cell expression of the enzyme and the estrogen receptor is correlated 668162 1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase breast cancer cell - 656788, 763397 1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase breast cancer cell 3beta-hydroxysteroid dehydrogenase type 1 693887 1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase breast cancer cell isozyme 3beta-HSD1 662371 1.1.1.188 prostaglandin-F synthase breast cancer cell 18fold increase in the median AKR1C3 mRNA levels in breast cancer patients as compared to those without disease 697271 1.1.1.188 prostaglandin-F synthase breast cancer cell of invasive ductal carcinoma of the breast, immunohistochemical analysis 740999 1.1.1.205 IMP dehydrogenase breast cancer cell - 761611 1.1.1.213 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) breast cancer cell - 675678 1.1.1.27 L-lactate dehydrogenase breast cancer cell - 740255 1.1.1.27 L-lactate dehydrogenase breast cancer cell normal and malignant human breast tissues. The enzyme is highly expressed in breast 740253 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase breast cancer cell 17beta-HSD7 is amplified in primary and progressive breast cancer 763396 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase breast cancer cell 3beta-HSD1 is selectively expressed in human placenta, mammary glands and breast tumors in women 763397 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase breast cancer cell expression of 3beta-hydroxysteroid dehydrogenase type 1 (HSD3B1) in breast cancer is associated with shorter recurrence-free survival, and genetic or pharmacologic inhibition of HSD3B1 reduced colony formation and xenograft growth 763404 1.1.1.270 3beta-hydroxysteroid 3-dehydrogenase breast cancer cell selective expression of 3beta-HSD1 725813 1.1.1.357 3alpha-hydroxysteroid 3-dehydrogenase breast cancer cell - 740017 1.1.1.37 malate dehydrogenase breast cancer cell - 760668 1.1.1.40 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) breast cancer cell - 761332 1.1.1.50 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) breast cancer cell - 740017 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase breast cancer cell - 761900 1.1.1.62 17beta-estradiol 17-dehydrogenase breast cancer cell - 685545, 711649, 713021, 726302, 740542, 740839, 740849, 761756, 761900 1.1.1.62 17beta-estradiol 17-dehydrogenase breast cancer cell 17beta-HSD1 is overexpressed in many breast tumors 688272 1.1.1.62 17beta-estradiol 17-dehydrogenase breast cancer cell the inhibition of the enzyme (17beta-HSD7) constitutes the basis of breast cancer cell proliferation 761756 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) breast cancer cell - 287331 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase breast cancer cell - 659398 1.13.11.33 arachidonate 15-lipoxygenase breast cancer cell - 676925 1.13.11.53 acireductone dioxygenase (Ni2+-requiring) breast cancer cell - 764226 1.14.11.16 peptide-aspartate beta-dioxygenase breast cancer cell - 742572 1.14.11.16 peptide-aspartate beta-dioxygenase breast cancer cell highly expressed 439254 1.14.11.2 procollagen-proline 4-dioxygenase breast cancer cell P4HA2 mRNA levels are significantly upregulated in breast cancer compared to normal mammary tissue 744594 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase breast cancer cell - 745919 1.14.11.4 procollagen-lysine 5-dioxygenase breast cancer cell - 725955 1.14.11.53 mRNA N6-methyladenine demethylase breast cancer cell - 739559, 765377 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase breast cancer cell - 701223 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase breast cancer cell - 711677, 756531 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase breast cancer cell high expression level of JARID1B 711581 1.14.11.7 procollagen-proline 3-dioxygenase breast cancer cell - 697017 1.14.13.8 flavin-containing monooxygenase breast cancer cell - 673313 1.14.14.18 heme oxygenase (biliverdin-producing) breast cancer cell - 728211 1.14.15.18 calcidiol 1-monooxygenase breast cancer cell - 671357, 695621 1.14.15.18 calcidiol 1-monooxygenase breast cancer cell the enzyme expression is reduced in breast cancer cell specimen compared to healthy breast tissue 672857 1.14.19.17 sphingolipid 4-desaturase breast cancer cell - 744398, 744686 1.15.1.1 superoxide dismutase breast cancer cell harbors MnSOD with the ala16val polymorphism 716197 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) breast cancer cell - 743173 1.2.1.3 aldehyde dehydrogenase (NAD+) breast cancer cell - 697114 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase breast cancer cell - 675897 1.3.1.1 dihydropyrimidine dehydrogenase (NAD+) breast cancer cell - 686604, 688302, 689367 1.4.3.13 protein-lysine 6-oxidase breast cancer cell - 687920, 713156 1.4.3.13 protein-lysine 6-oxidase breast cancer cell circulating 700903 1.4.3.13 protein-lysine 6-oxidase breast cancer cell hypoxic 697071 1.4.3.13 protein-lysine 6-oxidase breast cancer cell lymph node-negative breast adenocarcinoma cell 685957 1.5.1.2 pyrroline-5-carboxylate reductase breast cancer cell - 762877 1.5.3.13 N1-acetylpolyamine oxidase breast cancer cell - 703028 1.5.3.16 spermine oxidase breast cancer cell - 690800, 711592 1.6.3.1 NAD(P)H oxidase (H2O2-forming) breast cancer cell - 742556 1.8.1.9 thioredoxin-disulfide reductase breast cancer cell - 675915 1.8.3.2 thiol oxidase breast cancer cell expression analysis of a panel of cDNAs derived from 50 clinically-graded normal and malignant breast tissue samples for the expression of QSOX1 mRNAs, significant correlation between relative transcript level and clinical grade malignant breast tumors 743627 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase breast cancer cell - 704546 2.1.1.17 phosphatidylethanolamine N-methyltransferase breast cancer cell - 697843 2.1.1.220 tRNA (adenine58-N1)-methyltransferase breast cancer cell - 721024 2.1.1.244 protein N-terminal methyltransferase breast cancer cell - 736919 2.1.1.348 mRNA m6A methyltransferase breast cancer cell - 756331 2.1.1.355 [histone H3]-lysine9 N-trimethyltransferase breast cancer cell - 755156 2.1.1.357 [histone H3]-lysine36 N-dimethyltransferase breast cancer cell - 753720 2.1.1.361 [histone H4]-lysine20 N-methyltransferase breast cancer cell - 753133 2.1.1.56 mRNA (guanine-N7)-methyltransferase breast cancer cell - 757896 2.1.1.6 catechol O-methyltransferase breast cancer cell - 658443, 702678 2.1.2.1 glycine hydroxymethyltransferase breast cancer cell expression patterns of SHMT2 in 76 breast cancer patients after modified radical mastectomy, immunohistochemic analysis, SHMT2 is highly expressed in breast cancer cells, and the expression level of SHMT2 is positively correlated with breast cancer grade 736925 2.1.2.2 phosphoribosylglycinamide formyltransferase 1 breast cancer cell - 756648 2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase breast cancer cell - 756648 2.2.1.1 transketolase breast cancer cell TKTL1 expression in 86% of breast cancer specimens with 45% showing high expression levels 694502 2.3.1.135 phosphatidylcholine-retinol O-acyltransferase breast cancer cell neoplastic and adjacent, non-neoplastic glandular breast tissue specimens from human patients, expression analysis, reduced enzyme expression, LRAT protein progressively decreases with a reduction in the degree of tumor differentiation in invasive breast carcinomas, overview 674069 2.3.1.21 carnitine O-palmitoyltransferase breast cancer cell - 757235 2.3.1.24 sphingosine N-acyltransferase breast cancer cell isozymes CerS2 (EC 2.3.1.297) and CerS6 (EC 2.3.1.24) mRNA is significantly elevated in breast cancer tissue compared to normal tissue, with approximately half of the individuals showing elevated CerS2 and CerS6 mRNA. A significant correlation is found between CerS2 and CerS6 isozyme expression, and between isozymes CerS4 (EC 2.3.1.24) and CerS2/CerS6 expression 752644 2.3.1.291 sphingoid base N-palmitoyltransferase breast cancer cell - 752733 2.3.1.297 very-long-chain ceramide synthase breast cancer cell isozymes CerS2 (EC 2.3.1.297) and CerS6 (EC 2.3.1.24) mRNA is significantly elevated in breast cancer tissue compared to normal tissue, with approximately half of the individuals showing elevated CerS2 and CerS6 mRNA. A significant correlation is found between CerS2 and CerS6 isozyme expression, and between isozymes CerS4 (EC 2.3.1.24) and CerS2/CerS6 expression 752644 2.3.1.45 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase breast cancer cell - 677235 2.3.1.48 histone acetyltransferase breast cancer cell - 703846, 735352, 756658, 756850, 758109 2.3.1.5 arylamine N-acetyltransferase breast cancer cell - 735771, 735849, 756146 2.3.1.5 arylamine N-acetyltransferase breast cancer cell methylation status and the transcriptional activity of NAT1 in breast cancer tissues: methylation of NAT1 gene is identified in 39 of the breast carcinomas (54.2%), 23 normal (76.7%) and 25 benign breast tissue samples (80.6%). Breast cancer tissues show significantly lower methylation rates of the NAT1 promoters than the normal and benign tissues. Cancer tissues show lower methylation density rates than normal and benign breast tissues. Tissues that show aberrant methylation of NAT1 show significantly less mRNA expression compared with the unmethylated cases. 20 cancers from the methylated group show positive staining for the estrogen receptor (ER) (51.3%), while 72.7% from the unmethylated group stain positive 689296 2.3.1.5 arylamine N-acetyltransferase breast cancer cell NAT1 is overexpressed in estrogen receptor-positive breast cancer 686256 2.3.1.5 arylamine N-acetyltransferase breast cancer cell patients with ductal carcinoma 676155 2.3.1.57 diamine N-acetyltransferase breast cancer cell - 756851 2.3.1.57 diamine N-acetyltransferase breast cancer cell in breast tumors, SSAT is increased contributing to an increase in acetylated polyamines 701622 2.3.1.85 fatty-acid synthase system breast cancer cell - 704079, 705999 2.3.1.B43 protein-lysine desuccinylase (NAD+) breast cancer cell - 758247 2.3.1.B46 1-acylglycerophosphatidylinositol O-acyltransferase breast cancer cell - 757632 2.3.2.13 protein-glutamine gamma-glutamyltransferase breast cancer cell MDA-MB-231 (doxorubicin resistant) human breast cancer cell 685934 2.3.2.2 gamma-glutamyltransferase breast cancer cell - 694485 2.4.1.102 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase breast cancer cell - 759882 2.4.1.150 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase breast cancer cell GCNT2 is overexpressed in highly metastatic breast cancer cell lines. GCNT2 expression is also significantly correlated to the metastatic phenotype in breast tumor samples 758992 2.4.1.152 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase breast cancer cell - 735901 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase breast cancer cell - 693867 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase breast cancer cell epithelial and metastatic 758997 2.4.1.212 hyaluronan synthase breast cancer cell - 736064, 736145 2.4.1.222 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase breast cancer cell manic fringe is highly expressed in claudin-low breast cancer 735881 2.4.1.313 protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase breast cancer cell - 725164 2.4.1.80 ceramide glucosyltransferase breast cancer cell - 722787, 736201 2.4.2.12 nicotinamide phosphoribosyltransferase breast cancer cell - 735872 2.4.2.3 uridine phosphorylase breast cancer cell - 705806