1.1.1.135 GDP-6-deoxy-D-talose 4-dehydrogenase fibroblast cultured skin fibroblast 654167 1.1.1.146 11beta-hydroxysteroid dehydrogenase fibroblast isoform 11betaHSD1 741066 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) fibroblast amniotic, cell culture 286016 1.1.1.153 sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) fibroblast dermal, cell culture 286017 1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase fibroblast - 286121, 286123, 697369, 711851 1.1.1.188 prostaglandin-F synthase fibroblast - 740414 1.1.1.21 aldose reductase fibroblast - 697266 1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase fibroblast - 686162, 761165 1.1.1.211 long-chain-3-hydroxyacyl-CoA dehydrogenase fibroblast skin fibroblast 656815 1.1.1.22 UDP-glucose 6-dehydrogenase fibroblast primary fivbroblast 761985 1.1.1.31 3-hydroxyisobutyrate dehydrogenase fibroblast - 670284 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH) fibroblast - 695855 1.1.1.37 malate dehydrogenase fibroblast dermal, activity of MDH1 is reduced in old human dermal fibroblasts 723540 1.1.1.49 glucose-6-phosphate dehydrogenase (NADP+) fibroblast G6PD deficiency is associated with premature senescence of human fibroblasts 689997 1.1.1.8 glycerol-3-phosphate dehydrogenase (NAD+) fibroblast adipofibroblast, embryonic cell culture, up to 10fold increase of activity in presence of chicken serum, further increase in presence of embryonic chicken serum 657144 1.1.1.95 phosphoglycerate dehydrogenase fibroblast skin-derived 698189 1.1.1.96 diiodophenylpyruvate reductase fibroblast - 287552 1.1.99.2 L-2-hydroxyglutarate dehydrogenase fibroblast - 699377 1.1.99.24 hydroxyacid-oxoacid transhydrogenase fibroblast of healthy subjects and patients with D-2-hydroxyglutaric aciduria 675230 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase fibroblast - 674370 1.11.1.12 phospholipid-hydroperoxide glutathione peroxidase fibroblast mouse embryonic fibroblasts 764701 1.11.1.6 catalase fibroblast - 677210 1.13.11.12 linoleate 13S-lipoxygenase fibroblast - 765470 1.13.11.31 arachidonate 12-lipoxygenase fibroblast - 765070, 765470 1.13.11.33 arachidonate 15-lipoxygenase fibroblast - 765470 1.13.11.33 arachidonate 15-lipoxygenase fibroblast 15-LOX-1 706877 1.13.11.33 arachidonate 15-lipoxygenase fibroblast low expression 706579 1.13.11.33 arachidonate 15-lipoxygenase fibroblast rheumatoid arthritis tissue 701978 1.13.11.52 indoleamine 2,3-dioxygenase fibroblast - 395502, 711952, 713591 1.13.11.52 indoleamine 2,3-dioxygenase fibroblast diploid fibroblast cells FS-4 395503 1.14.11.2 procollagen-proline 4-dioxygenase fibroblast - 439213, 439242, 439243 1.14.11.2 procollagen-proline 4-dioxygenase fibroblast adult and fetal skin, the type I enzyme is the main enzyme form 439243 1.14.11.2 procollagen-proline 4-dioxygenase fibroblast foreskin 439247 1.14.11.2 procollagen-proline 4-dioxygenase fibroblast gingival fibroblast 684766 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase fibroblast embryonic 700374 1.14.11.27 [histone H3]-dimethyl-L-lysine36 demethylase fibroblast MEF 754726 1.14.11.30 hypoxia-inducible factor-asparagine dioxygenase fibroblast embryonic fibriblast 764438 1.14.11.4 procollagen-lysine 5-dioxygenase fibroblast - -, 673470, 675763, 698942, 726309, 745323, 746479 1.14.11.4 procollagen-lysine 5-dioxygenase fibroblast from fibrotic skin of patients with systemic sclerosis 659266 1.14.11.4 procollagen-lysine 5-dioxygenase fibroblast of skin, expression only of LH2long 659845 1.14.11.4 procollagen-lysine 5-dioxygenase fibroblast skin 659652, 745334, 745445 1.14.11.4 procollagen-lysine 5-dioxygenase fibroblast skin and embryonic -, 746171 1.14.11.4 procollagen-lysine 5-dioxygenase fibroblast synovial osteoarthritic 724702 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase fibroblast - 755188 1.14.11.65 [histone H3]-dimethyl-L-lysine9 demethylase fibroblast primary 701223 1.14.11.66 [histone H3]-trimethyl-L-lysine9 demethylase fibroblast in wild-type fibroblasts, the chromatin of ribosomal genes, which is dense with H3K9 methylation, lacks JMJD2b-GFP-1086, while mutant and truncated forms of JMJD2b densely occupie the nucleolar compartment 712775 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase fibroblast - 725484 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase fibroblast embryonic 685984 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase fibroblast MEF 754726 1.14.11.67 [histone H3]-trimethyl-L-lysine4 demethylase fibroblast mouse embryonic fibroblasts, MEFs 744866 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase fibroblast - 753462, 755060 1.14.11.68 [histone H3]-trimethyl-L-lysine27 demethylase fibroblast UTX is enriched around the transcription start sites of many HOX genes in primary human fibroblasts 754877 1.14.11.69 [histone H3]-trimethyl-L-lysine36 demethylase fibroblast embryonic fibroblast 755480 1.14.11.7 procollagen-proline 3-dioxygenase fibroblast - 672947, 698181 1.14.11.7 procollagen-proline 3-dioxygenase fibroblast isozyme P3H1 697189 1.14.11.7 procollagen-proline 3-dioxygenase fibroblast isozyme P3H2 697189 1.14.11.7 procollagen-proline 3-dioxygenase fibroblast isozyme P3H3 697189 1.14.11.B19 [histone H3]-trimethyl-L-lysine56 demethylase fibroblast embryonic fibroblast cell 755194 1.14.14.18 heme oxygenase (biliverdin-producing) fibroblast - 687570 1.14.14.18 heme oxygenase (biliverdin-producing) fibroblast dermal 687555 1.14.16.4 tryptophan 5-monooxygenase fibroblast dermal 658187 1.14.18.9 4alpha-methylsterol monooxygenase fibroblast - 728037 1.14.18.9 4alpha-methylsterol monooxygenase fibroblast inhibition of sterol C4methyl oxidase induces activation of the cell cycle 727093 1.14.19.3 acyl-CoA 6-desaturase fibroblast skin fibroblast 438421 1.14.99.1 prostaglandin-endoperoxide synthase fibroblast - 438393 1.14.99.66 [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase fibroblast - 755188 1.17.4.1 ribonucleoside-diphosphate reductase fibroblast - 437909 1.17.4.2 ribonucleoside-triphosphate reductase (thioredoxin) fibroblast isozymes R2 and p53R2 715583 1.17.4.4 vitamin-K-epoxide reductase (warfarin-sensitive) fibroblast dermal, low expression rate 675907 1.2.1.104 pyruvate dehydrogenase system fibroblast - 662948, 699383 1.2.1.105 2-oxoglutarate dehydrogenase system fibroblast - 654854, 671961 1.2.1.12 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) fibroblast in both fetal and senior cells, considerable GAPDH is present in intracellular domains characterized by significantly reduced catalysis. Human cells contain significant intracellular levels of enzymatically inactive GAPDH which is age-independent 654849 1.2.1.31 L-aminoadipate-semialdehyde dehydrogenase fibroblast - 712017 1.2.1.48 long-chain-aldehyde dehydrogenase fibroblast - 656817, 725656 1.2.4.1 pyruvate dehydrogenase (acetyl-transferring) fibroblast - 710839 1.3.1.21 7-dehydrocholesterol reductase fibroblast - 349276 1.3.1.21 7-dehydrocholesterol reductase fibroblast of healthy persons, heterozygous persons, and Smith-Lemli-Opitz syndrome patients 656818 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) fibroblast - 684907 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) fibroblast cultured 396207 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) fibroblast cultured female and male genital skin fibroblasts 396221 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) fibroblast foreskin, Hs68 656656 1.3.1.24 biliverdin reductase fibroblast - 724924 1.3.1.6 fumarate reductase (NADH) fibroblast - 713389 1.3.1.70 DELTA14-sterol reductase fibroblast of an 18-weeks-old fetus with autosomal recessive HEM/Greenberg skeletal dysplasia showing enzyme-deficiency 654166 1.3.1.72 DELTA24-sterol reductase fibroblast fibroblast from skin 288497 1.3.3.4 protoporphyrinogen oxidase fibroblast - 390981 1.3.3.6 acyl-CoA oxidase fibroblast - 684293, 712822 1.3.8.1 short-chain acyl-CoA dehydrogenase fibroblast - 687031, 689021, 712126 1.3.8.4 isovaleryl-CoA dehydrogenase fibroblast - 391206, 391212, 391214, 699381 1.3.8.6 glutaryl-CoA dehydrogenase (ETF) fibroblast - 688177, 689338, 713046 1.3.8.6 glutaryl-CoA dehydrogenase (ETF) fibroblast cultured 391410 1.3.8.7 medium-chain acyl-CoA dehydrogenase fibroblast - 688185 1.3.8.8 long-chain acyl-CoA dehydrogenase fibroblast - 394665, 676027, 684281, 686160 1.3.8.8 long-chain acyl-CoA dehydrogenase fibroblast normal and VLCAD-deficient individuals 673935 1.3.99.23 all-trans-retinol 13,14-reductase fibroblast - 686872, 763769 1.3.99.5 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) fibroblast from all areas 713519 1.4.3.13 protein-lysine 6-oxidase fibroblast - 391742, 685981, 687597, 687919, 696449 1.4.3.13 protein-lysine 6-oxidase fibroblast secretion of free soluble enzyme 659558 1.4.3.4 monoamine oxidase fibroblast MAO A is prevalent in fibroblasts and placental tissue 684241 1.4.3.4 monoamine oxidase fibroblast of blood vessels 655721 1.4.4.2 glycine dehydrogenase (aminomethyl-transferring) fibroblast - 656820, 724197 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+) fibroblast - 392077, 392084, 392085, 392092, 671588 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+) fibroblast embryo fibroblast 392077 1.5.1.15 methylenetetrahydrofolate dehydrogenase (NAD+) fibroblast primary embryonic 656129 1.5.1.2 pyrroline-5-carboxylate reductase fibroblast - 392128 1.5.1.3 dihydrofolate reductase fibroblast cultured 3T6 mouse embryo fibroblasts 392270 1.5.1.34 6,7-dihydropteridine reductase fibroblast cell culture 484975 1.6.1.2 NAD(P)+ transhydrogenase (Re/Si-specific) fibroblast - 743069 1.6.2.4 NADPH-hemoprotein reductase fibroblast - 658621 1.6.3.1 NAD(P)H oxidase (H2O2-forming) fibroblast - -, 688937, 725065 1.6.3.1 NAD(P)H oxidase (H2O2-forming) fibroblast adventitial and cardial 724778 1.6.3.1 NAD(P)H oxidase (H2O2-forming) fibroblast L-carnitine inhibits angiotensin II increased NADPH oxidase activity and intracellular ROS levels in cardiac fibroblasts 699700 1.6.3.1 NAD(P)H oxidase (H2O2-forming) fibroblast primary culture of adventitial fibroblast 685975 1.6.5.4 monodehydroascorbate reductase (NADH) fibroblast normal and virus-transformed 392744 1.8.1.4 dihydrolipoyl dehydrogenase fibroblast - 673943 1.8.1.9 thioredoxin-disulfide reductase fibroblast - 675936 1.8.3.1 sulfite oxidase fibroblast - 741618, 765392 1.8.3.2 thiol oxidase fibroblast - 659861, 765727 1.8.3.2 thiol oxidase fibroblast embroynic fibroblast 724952 1.8.3.2 thiol oxidase fibroblast high expression level of QSOX1 657645 1.8.3.7 formylglycine-generating enzyme fibroblast - 742435, 742833 1.8.4.11 peptide-methionine (S)-S-oxide reductase fibroblast - 697860 1.8.4.11 peptide-methionine (S)-S-oxide reductase fibroblast cell line WI-38, young and old cells, enzyme expression pattern during cell development, senescent cells show decreased enzyme expression and activity 658217 1.8.4.11 peptide-methionine (S)-S-oxide reductase fibroblast overexpression of MsrA protects immortalized WI-38 SV40 human fibroblasts against H2O2–mediated oxidative stress by reducing the amount of intracellular reactive oxygen species and the extent of irreversible protein oxidative damage 686598 1.8.4.11 peptide-methionine (S)-S-oxide reductase fibroblast WI-38 658729 1.8.4.12 peptide-methionine (R)-S-oxide reductase fibroblast cell line WI-38, young and old cells, enzyme expression pattern during cell development, senescent cells show decreased enzyme expression and activity 658217 1.8.4.12 peptide-methionine (R)-S-oxide reductase fibroblast WI-38 658729 1.8.5.1 glutathione dehydrogenase (ascorbate) fibroblast - 394019 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase fibroblast - 485020, 485024 2.1.1.13 methionine synthase fibroblast expression of both active 140 kDa form and the inactive truncated 124 kDa isoform 756088 2.1.1.2 guanidinoacetate N-methyltransferase fibroblast - 689013 2.1.1.2 guanidinoacetate N-methyltransferase fibroblast primary 733954 2.1.1.202 multisite-specific tRNA:(cytosine-C5)-methyltransferase fibroblast - 758103, 758477 2.1.1.204 tRNA (cytosine38-C5)-methyltransferase fibroblast - -, 736018 2.1.1.233 [phosphatase 2A protein]-leucine-carboxy methyltransferase fibroblast embryonic 751067 2.1.1.309 18S rRNA (guanine1575-N7)-methyltransferase fibroblast - 736779 2.1.1.321 type III protein arginine methyltransferase fibroblast embryonic 755900 2.1.1.355 [histone H3]-lysine9 N-trimethyltransferase fibroblast embryonic fibrobast 756364 2.1.1.355 [histone H3]-lysine9 N-trimethyltransferase fibroblast embryonic fibroblast cell 672911 2.1.1.361 [histone H4]-lysine20 N-methyltransferase fibroblast - 753196 2.1.1.364 [histone H3]-lysine4 N-methyltransferase fibroblast - 759536 2.1.1.367 [histone H3]-lysine9 N-methyltransferase fibroblast embryonic fibroblast 756364 2.1.1.45 thymidylate synthase fibroblast - 485404, 757252 2.1.1.61 tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase fibroblast - 701608 2.1.1.63 methylated-DNA-[protein]-cysteine S-methyltransferase fibroblast - 485492, 673219 2.1.1.67 thiopurine S-methyltransferase fibroblast - 485528 2.1.4.1 glycine amidinotransferase fibroblast - 485967 2.3.1.108 alpha-tubulin N-acetyltransferase fibroblast - 757561 2.3.1.137 carnitine O-octanoyltransferase fibroblast skin fibroblast 486305 2.3.1.168 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase fibroblast - 644843 2.3.1.199 very-long-chain 3-oxoacyl-CoA synthase fibroblast - 735905 2.3.1.20 diacylglycerol O-acyltransferase fibroblast - 758179 2.3.1.21 carnitine O-palmitoyltransferase fibroblast - 659899, 705753, 736077, 737070 2.3.1.24 sphingosine N-acyltransferase fibroblast - -, 754360 2.3.1.250 [Wnt protein] O-palmitoleoyl transferase fibroblast - 733769, 734194, 734745 2.3.1.26 sterol O-acyltransferase fibroblast - 486677, 486693 2.3.1.42 glycerone-phosphate O-acyltransferase fibroblast - 687045 2.3.1.42 glycerone-phosphate O-acyltransferase fibroblast cell culture 486971 2.3.1.48 histone acetyltransferase fibroblast - 703846, 756418 2.3.1.48 histone acetyltransferase fibroblast primary dermal 706421 2.3.1.50 serine C-palmitoyltransferase fibroblast proliferating, neonatal, dermal 659621 2.3.1.57 diamine N-acetyltransferase fibroblast fetal 702136 2.3.1.57 diamine N-acetyltransferase fibroblast primary fetal fibroblasts 487267 2.3.1.57 diamine N-acetyltransferase fibroblast synovial fibroblasts from patients with rheumatoid arthritis or osteoarthritis 735576 2.3.1.6 choline O-acetyltransferase fibroblast lung, fetal lung fibroblasts, HFL-1 705317 2.3.1.61 dihydrolipoyllysine-residue succinyltransferase fibroblast - 487341 2.3.1.7 carnitine O-acetyltransferase fibroblast - -, 487416, 487428 2.3.1.78 heparan-alpha-glucosaminide N-acetyltransferase fibroblast primary fibroblast 756105 2.3.1.9 acetyl-CoA C-acetyltransferase fibroblast - 658880, 676035, 706822 2.3.1.97 glycylpeptide N-tetradecanoyltransferase fibroblast - 735616 2.3.2.13 protein-glutamine gamma-glutamyltransferase fibroblast primary foreskin fibroblast 659554 2.3.2.8 arginyltransferase fibroblast embryonic 488021 2.3.2.8 arginyltransferase fibroblast MEFs -, 758964 2.3.3.10 hydroxymethylglutaryl-CoA synthase fibroblast - 488111, 488113, 488114 2.4.1.109 dolichyl-phosphate-mannose-protein mannosyltransferase fibroblast dermal 710090 2.4.1.11 glycogen(starch) synthase fibroblast - 488440 2.4.1.134 galactosylxylosylprotein 3-beta-galactosyltransferase fibroblast - 735420 2.4.1.141 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase fibroblast - 639511 2.4.1.155 alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase fibroblast - 692524 2.4.1.174 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase fibroblast - 737300, 759329 2.4.1.175 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase fibroblast - 701456 2.4.1.175 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase fibroblast embryonic, expression level analysis for the splice variants CSS2A and CSS2B, overview -, 722689 2.4.1.212 hyaluronan synthase fibroblast - -, 659334, 695183, 736145, 737217 2.4.1.212 hyaluronan synthase fibroblast dermal -, 721994 2.4.1.212 hyaluronan synthase fibroblast dermal fibroblast 690807 2.4.1.212 hyaluronan synthase fibroblast HAS2 is suppressed in senescent fibroblasts, real time PCR enzyme expresion in fibrotic and senescent fibroblasts 736725 2.4.1.212 hyaluronan synthase fibroblast oral and dermal fibroblast 693001 2.4.1.212 hyaluronan synthase fibroblast skin fibroblast 736219 2.4.1.212 hyaluronan synthase fibroblast uterine cervical 657784 2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase fibroblast - 488953, 488955, 488957, 488962 2.4.1.224 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase fibroblast skin-derived 736621 2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase fibroblast - 687759 2.4.1.225 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase fibroblast skin-derived 736621 2.4.1.226 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase fibroblast - -, 722689 2.4.1.258 dolichyl-P-Man:Man5GlcNAc2-PP-dolichol alpha-1,3-mannosyltransferase fibroblast - 759330 2.4.1.259 dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase fibroblast - 707037 2.4.1.259 dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase fibroblast dermal fibroblast 736816 2.4.1.259 dolichyl-P-Man:Man6GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase fibroblast primary fibloblast 708614 2.4.1.260 dolichyl-P-Man:Man7GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase fibroblast primary fibroblasts obtained from skin biopsies 638310 2.4.1.261 dolichyl-P-Man:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase fibroblast - 707037 2.4.1.261 dolichyl-P-Man:Man8GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase fibroblast primary fibloblast 708614 2.4.1.267 dolichyl-P-Glc:Man9GlcNAc2-PP-dolichol alpha-1,3-glucosyltransferase fibroblast - 736204 2.4.1.274 glucosylceramide beta-1,4-galactosyltransferase fibroblast isoform beta4GalT5 works predominantly in mouse embryonic fibroblasts 736193 2.4.1.313 protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase fibroblast - 723906 2.4.1.50 procollagen galactosyltransferase fibroblast - 705703 2.4.1.66 procollagen glucosyltransferase fibroblast - 698942 2.4.1.66 procollagen glucosyltransferase fibroblast cultured skin fibroblasts 439149 2.4.1.66 procollagen glucosyltransferase fibroblast fetal lung WI-38 and IMR-90 diploid fibroblasts, in cell suspension culture 489282 2.4.1.79 globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase fibroblast cultured hamster cells, NIL-8 488622 2.4.1.87 N-acetyllactosaminide 3-alpha-galactosyltransferase fibroblast cultured from ear skin biopsies 736808 2.4.1.92 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase fibroblast - 735875 2.4.2.1 purine-nucleoside phosphorylase fibroblast - -, 760109 2.4.2.12 nicotinamide phosphoribosyltransferase fibroblast - 735872 2.4.2.12 nicotinamide phosphoribosyltransferase fibroblast diploid, GM 1362, from patient with Lesch-Nyhan disease 489740 2.4.2.12 nicotinamide phosphoribosyltransferase fibroblast enzyme and Sir2 expression levels 662306 2.4.2.14 amidophosphoribosyltransferase fibroblast - 489754 2.4.2.26 protein xylosyltransferase fibroblast cardiac fibroblast 687601 2.4.2.3 uridine phosphorylase fibroblast - 638457, 638542 2.4.2.30 NAD+ ADP-ribosyltransferase fibroblast - 675025 2.4.2.30 NAD+ ADP-ribosyltransferase fibroblast primary, from lung -, 671255 2.4.2.4 thymidine phosphorylase fibroblast - 705495 2.4.2.6 nucleoside deoxyribosyltransferase fibroblast - 674900 2.4.2.64 tRNA-guanosine34 queuine transglycosylase fibroblast L-M cell 758853 2.4.2.8 hypoxanthine phosphoribosyltransferase fibroblast - 662878 2.4.3.9 lactosylceramide alpha-2,3-sialyltransferase fibroblast contact-inhibited cell-line NIL-8 638785 2.4.99.18 dolichyl-diphosphooligosaccharide-protein glycotransferase fibroblast - 684282 2.5.1.16 spermidine synthase fibroblast embryo, 7 days old 639717 2.5.1.17 corrinoid adenosyltransferase fibroblast - 676023 2.5.1.22 spermine synthase fibroblast primary culture of embryonic fibroblast 489877 2.5.1.26 alkylglycerone-phosphate synthase fibroblast - 489892, 489893 2.5.1.39 4-hydroxybenzoate polyprenyltransferase fibroblast - 723246, 723550 2.5.1.39 4-hydroxybenzoate polyprenyltransferase fibroblast CoQ10 synthesis is significantly decreased in cultured skin fibroblasts of mutant S109N 738168 2.5.1.46 deoxyhypusine synthase fibroblast - -, 721984 2.5.1.59 protein geranylgeranyltransferase type I fibroblast - 675067 2.5.1.60 protein geranylgeranyltransferase type II fibroblast - 638598 2.5.1.87 ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] fibroblast - 738001 2.6.1.1 aspartate transaminase fibroblast 3T3-L1 cells, low activity 639866 2.6.1.13 ornithine aminotransferase fibroblast - 637136 2.6.1.16 glutamine-fructose-6-phosphate transaminase (isomerizing) fibroblast - 639928 2.6.1.42 branched-chain-amino-acid transaminase fibroblast - 640021, 640031 2.6.99.1 dATP(dGTP)-DNA purinetransferase fibroblast cultured 640204 2.7.1.1 hexokinase fibroblast - 760189 2.7.1.1 hexokinase fibroblast fibroblasts from patients with idiopathic pulmonary fibrosis exhibit an increased abundance of hexokinase 2 760189 2.7.1.107 diacylglycerol kinase (ATP) fibroblast - 737399 2.7.1.107 diacylglycerol kinase (ATP) fibroblast embryonic 737685 2.7.1.107 diacylglycerol kinase (ATP) fibroblast ras-transformed 640366 2.7.1.108 dolichol kinase fibroblast - 671201 2.7.1.108 dolichol kinase fibroblast dermal 696448 2.7.1.113 deoxyguanosine kinase fibroblast - 671890, 705750 2.7.1.113 deoxyguanosine kinase fibroblast from forearm skin 671890 2.7.1.113 deoxyguanosine kinase fibroblast genotyping of the enzyme splicing variants and mutants in fibroblast cell lines 723198 2.7.1.137 phosphatidylinositol 3-kinase fibroblast - 640881, 709772 2.7.1.137 phosphatidylinositol 3-kinase fibroblast embryonic fibroblast cells 722666 2.7.1.137 phosphatidylinositol 3-kinase fibroblast from embryo 640884 2.7.1.137 phosphatidylinositol 3-kinase fibroblast Swiss 3T3 fibroblast 640870 2.7.1.138 ceramide kinase fibroblast - -, 671789, 673703, 738825 2.7.1.138 ceramide kinase fibroblast renal 738014 2.7.1.14 sedoheptulokinase fibroblast - 738810 2.7.1.149 1-phosphatidylinositol-5-phosphate 4-kinase fibroblast - 393080 2.7.1.151 inositol-polyphosphate multikinase fibroblast embryonic 673015 2.7.1.151 inositol-polyphosphate multikinase fibroblast embryonic fibroblast cell 721987 2.7.1.151 inositol-polyphosphate multikinase fibroblast embryonic fibroblast cell from mice harboring a conditionally targeted IPMK allele 723641 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase fibroblast - 708670 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase fibroblast embryonic 709343 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase fibroblast embryonic fibroblast cell culture 662846 2.7.1.153 phosphatidylinositol-4,5-bisphosphate 3-kinase fibroblast embryonic fibroblast cells 722666 2.7.1.171 protein-fructosamine 3-kinase fibroblast cultured fibroblasts treated with conditions mimicking the hormonal and biochemical profile of the diabetic state show no changes in fructosamine-3-kinase expression relative to untreated cells. FN3K acts as protein repair enzyme and is expressed constitutively in human cells independently of some of the variables altered in the diabetic state 707351 2.7.1.21 thymidine kinase fibroblast embryonal 641139 2.7.1.22 ribosylnicotinamide kinase fibroblast - -, 758846 2.7.1.23 NAD+ kinase fibroblast - 641193, 641202 2.7.1.23 NAD+ kinase fibroblast from embryo 641202 2.7.1.30 glycerol kinase fibroblast cultured 661655 2.7.1.32 choline kinase fibroblast - 674066 2.7.1.36 mevalonate kinase fibroblast primary skin fibrobasts from healthy donors and patients with Zellweger syndrome 662499 2.7.1.40 pyruvate kinase fibroblast - 707158 2.7.1.40 pyruvate kinase fibroblast vultured skin fibroblast 691080 2.7.1.56 1-phosphofructokinase fibroblast - 737595 2.7.1.60 N-acylmannosamine kinase fibroblast cultured cells 661840 2.7.1.67 1-phosphatidylinositol 4-kinase fibroblast - 759586 2.7.1.67 1-phosphatidylinositol 4-kinase fibroblast PI4KIIalpha normally present both in perinuclear and peripheral organelles is substantially decreased in the peripheral membranes of AP-3-deficient mocha fibroblasts 662815 2.7.1.68 1-phosphatidylinositol-4-phosphate 5-kinase fibroblast - 660641, 675019, 676808 2.7.1.78 polynucleotide 5'-hydroxyl-kinase fibroblast - 729562 2.7.1.91 sphingosine kinase fibroblast - 671356, 674084, 703087 2.7.1.91 sphingosine kinase fibroblast SPHK2 is expressed in the synovial fibroblasts of the synovial tissues obtained from the knee joints of rheumatiod patients. In the cultured synovial fibroblasts from these patients, SPHK2 is more highly expressed than that in the human macrophage cell line, THP-1 and human dermal fibroblasts. SPHK2 is expressed in and around the nucleus and transferred to the cytoplasm and cell surface by the administration of epidermal growth factor, associated with the increased expression of sphingosine 1-phosphate. A sphingosine analogue, FTY720, which is activated by phosphorylation specifically by SPHK2, mediates apoptotic signaling of the cultured synovial fibroblasts 706074 2.7.10.1 receptor protein-tyrosine kinase fibroblast - 672957, 673210, 674526 2.7.10.1 receptor protein-tyrosine kinase fibroblast embryonic primary and immortalized 662178 2.7.10.1 receptor protein-tyrosine kinase fibroblast lung 660727 2.7.10.2 non-specific protein-tyrosine kinase fibroblast - 490144, 661273, 673700, 676266 2.7.10.2 non-specific protein-tyrosine kinase fibroblast endothelial 674526 2.7.10.2 non-specific protein-tyrosine kinase fibroblast PYK2 673223 2.7.11.1 non-specific serine/threonine protein kinase fibroblast - 491060, 491916, 532759, 672919 2.7.11.1 non-specific serine/threonine protein kinase fibroblast embryonic 743270 2.7.11.1 non-specific serine/threonine protein kinase fibroblast IR fibroblasts 662053 2.7.11.10 IkappaB kinase fibroblast - 662570, 663441, 671920 2.7.11.10 IkappaB kinase fibroblast adult and embryonic 663441 2.7.11.10 IkappaB kinase fibroblast embryonic 662942 2.7.11.10 IkappaB kinase fibroblast mouse embryonic fibrblasts MEF 675202 2.7.11.10 IkappaB kinase fibroblast mouse embryonic fibroblasts MEF 674835 2.7.11.10 IkappaB kinase fibroblast mouse embryonic fibroblasts, MEF 676147, 677127 2.7.11.10 IkappaB kinase fibroblast murine embryonic fibroblast, MEF 722119 2.7.11.11 cAMP-dependent protein kinase fibroblast - -, 721701 2.7.11.11 cAMP-dependent protein kinase fibroblast adut skin and NHDF neonatal human dermal fibroblasts 721701 2.7.11.12 cGMP-dependent protein kinase fibroblast - 661456 2.7.11.12 cGMP-dependent protein kinase fibroblast in normal diploid fibroblasts, the gene is constitutively expressed during cell-cycle and population doubling levels 491009 2.7.11.13 protein kinase C fibroblast - 491041, 662271, 662293, 671952, 673016, 676029, 692635 2.7.11.13 protein kinase C fibroblast isozyme beta 661849 2.7.11.13 protein kinase C fibroblast primary from fetal lung 673479 2.7.11.15 beta-adrenergic-receptor kinase fibroblast - 725420 2.7.11.17 Ca2+/calmodulin-dependent protein kinase fibroblast 1HIRc B cells (overexpressing the human insulin receptor), embryonic cell line 3Y1, both with elevated kinase activity after treatment with mitogens, e.g. insulin or epidermal growth factor 490760, 490761 2.7.11.17 Ca2+/calmodulin-dependent protein kinase fibroblast CaM-KI 664865 2.7.11.18 myosin-light-chain kinase fibroblast from embryo 491242 2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase fibroblast embryonic fibroblast cell line 672978 2.7.11.2 [pyruvate dehydrogenase (acetyl-transferring)] kinase fibroblast in the non small cell lung tumor-supporting stroma, reduced expression of PDK1, high PDH activity 662948 2.7.11.20 elongation factor 2 kinase fibroblast - 686003 2.7.11.20 elongation factor 2 kinase fibroblast mouse embryonic fibroblasts, MEFs 740996 2.7.11.21 polo kinase fibroblast - 661532 2.7.11.22 cyclin-dependent kinase fibroblast - 491585, 693903 2.7.11.22 cyclin-dependent kinase fibroblast cells infected with the human cytomegalovirus HCMV 666185 2.7.11.22 cyclin-dependent kinase fibroblast foreskin fibroblasts 666186 2.7.11.22 cyclin-dependent kinase fibroblast primary diploid fibroblast 679989 2.7.11.23 [RNA-polymerase]-subunit kinase fibroblast foreskin fibroblasts 662740 2.7.11.23 [RNA-polymerase]-subunit kinase fibroblast of foreskin 681696 2.7.11.24 mitogen-activated protein kinase fibroblast - 665052, 740424 2.7.11.24 mitogen-activated protein kinase fibroblast L929sA fibroblast 702156 2.7.11.25 mitogen-activated protein kinase kinase kinase fibroblast - 664742, 681023, 682954, 695197 2.7.11.25 mitogen-activated protein kinase kinase kinase fibroblast constitutive c-Mos expression transforms fibroblasts 682213 2.7.11.30 receptor protein serine/threonine kinase fibroblast - 664318, 665554 2.7.11.31 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase fibroblast - 644970, 690725 2.7.11.4 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase fibroblast - 662283 2.7.12.2 mitogen-activated protein kinase kinase fibroblast - 682214 2.7.3.2 creatine kinase fibroblast - 737427 2.7.4.11 (deoxy)adenylate kinase fibroblast - 642684 2.7.4.2 phosphomevalonate kinase fibroblast endogenously expressed human phosphomevalonate kinase and overexpressed human phosphomevalonate kinase 662590 2.7.4.3 adenylate kinase fibroblast - 705851 2.7.4.6 nucleoside-diphosphate kinase fibroblast - 692214 2.7.4.8 guanylate kinase fibroblast strain L60TM, a subline of Earle's L-strain, i.e. L-cells 642684 2.7.4.9 dTMP kinase fibroblast - 759870 2.7.6.1 ribose-phosphate diphosphokinase fibroblast - 671202, 721253 2.7.7.12 UDP-glucose-hexose-1-phosphate uridylyltransferase fibroblast - 642844 2.7.7.12 UDP-glucose-hexose-1-phosphate uridylyltransferase fibroblast primary skin fibroblast 737614 2.7.7.14 ethanolamine-phosphate cytidylyltransferase fibroblast embryonic -, 722415 2.7.7.15 choline-phosphate cytidylyltransferase fibroblast - 721712, 761500 2.7.7.15 choline-phosphate cytidylyltransferase fibroblast embryonic 761981 2.7.7.15 choline-phosphate cytidylyltransferase fibroblast fetal lung-derived 642892 2.7.7.19 polynucleotide adenylyltransferase fibroblast primary foreskin fibroblasts 723267 2.7.7.2 FAD synthase fibroblast - -, 738594 2.7.7.48 RNA-directed RNA polymerase fibroblast - 702647 2.7.7.6 DNA-directed RNA polymerase fibroblast - 701717, 705982, 738010 2.7.7.6 DNA-directed RNA polymerase fibroblast IMR90 fibroblasts 723636 2.7.7.7 DNA-directed DNA polymerase fibroblast - 703443 2.7.7.72 CCA tRNA nucleotidyltransferase fibroblast - 739230 2.7.7.72 CCA tRNA nucleotidyltransferase fibroblast TRNT1 protein levels are 10fold lower in muscle than in fibroblasts 738350 2.7.7.86 cyclic GMP-AMP synthase fibroblast - 761796 2.7.7.86 cyclic GMP-AMP synthase fibroblast immortalized 82-6 fibroblasts 761514 2.7.8.11 CDP-diacylglycerol-inositol 3-phosphatidyltransferase fibroblast NIH3T3 cells 645321 2.7.8.17 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase fibroblast - 135495, 645375, 671199 2.7.8.17 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase fibroblast high expression level 761904 2.7.8.17 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase fibroblast normal, no activity in I-cell fibroblasts 639426 2.7.8.19 UDP-glucose-glycoprotein glucose phosphotransferase fibroblast normal and I-cell 639426 2.7.8.27 sphingomyelin synthase fibroblast isozymes SMS1 and SMS2 692991 2.7.8.29 L-serine-phosphatidylethanolamine phosphatidyltransferase fibroblast - 741056 2.7.8.3 ceramide cholinephosphotransferase fibroblast - 645385 2.8.1.2 3-mercaptopyruvate sulfurtransferase fibroblast - 760675 2.8.1.7 cysteine desulfurase fibroblast cultured fibroblast 674628 2.8.2.17 chondroitin 6-sulfotransferase fibroblast - 701610 2.8.2.17 chondroitin 6-sulfotransferase fibroblast dermal 701607 2.8.2.17 chondroitin 6-sulfotransferase fibroblast perivascular, epineurial and perineurial 675008 2.8.2.20 protein-tyrosine sulfotransferase fibroblast primary 676006 2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3 fibroblast - 760623 2.8.2.30 [heparan sulfate]-glucosamine 3-sulfotransferase 3 fibroblast primary corneal, 3-OST-3 expression analysis 675705 2.8.2.5 chondroitin 4-sulfotransferase fibroblast - 721529 2.8.2.7 UDP-N-acetylgalactosamine-4-sulfate sulfotransferase fibroblast - 645923 2.8.3.5 3-oxoacid CoA-transferase fibroblast - 645982, 645984, 645991, 645992, 676034 2.8.3.5 3-oxoacid CoA-transferase fibroblast from foreskin 705310 2.8.3.5 3-oxoacid CoA-transferase fibroblast of mutant enzyme R268H 694193 3.1.1.1 carboxylesterase fibroblast lung 728935 3.1.1.106 O-acetyl-ADP-ribose deacetylase fibroblast - 751012 3.1.1.13 sterol esterase fibroblast - 133841, 133842 3.1.1.32 phospholipase A1 fibroblast cultured cells 666965 3.1.1.4 phospholipase A2 fibroblast embryonic 750503 3.1.1.89 protein phosphatase methylesterase-1 fibroblast - 750553, 751067 3.1.1.89 protein phosphatase methylesterase-1 fibroblast embryonic 751932 3.1.11.7 adenosine-5'-diphospho-5'-[DNA] diphosphatase fibroblast - 750390, 750720 3.1.13.4 poly(A)-specific ribonuclease fibroblast - 670367 3.1.2.22 palmitoyl[protein] hydrolase fibroblast normal fibroblasts and infantile neuronal ceroid lipofuscinosis fibroblasts, deficient of PPT1 707557 3.1.21.10 crossover junction endodeoxyribonuclease fibroblast PSNG13, Bloom's syndrome-associated, BLM, helicase-deficient fibroblasts, PSNF5, BLM-complemented fibroblasts 683782 3.1.21.7 deoxyribonuclease V fibroblast - 730709 3.1.27.8 Ribonuclease V fibroblast dermal 730457 3.1.3.16 protein-serine/threonine phosphatase fibroblast - 654485, 664932, 709404 3.1.3.16 protein-serine/threonine phosphatase fibroblast SV40-transformed 665521 3.1.3.2 acid phosphatase fibroblast normal and mucolipidosis II fibroblasts 134719 3.1.3.34 deoxynucleotide 3'-phosphatase fibroblast - 81083 3.1.3.36 phosphoinositide 5-phosphatase fibroblast - 713723 3.1.3.4 phosphatidate phosphatase fibroblast - 663975, 707555, 709420 3.1.3.4 phosphatidate phosphatase fibroblast embryonic, derived from LPP-1 overexpression mutant and wild-type mice 663975 3.1.3.43 [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase fibroblast - 698173 3.1.3.48 protein-tyrosine-phosphatase fibroblast - 680916, 707865 3.1.3.48 protein-tyrosine-phosphatase fibroblast lung 710028 3.1.3.5 5'-nucleotidase fibroblast - 649280, 752251 3.1.3.53 [myosin-light-chain] phosphatase fibroblast embryonic, large myosin phosphatase target subunit MYPT 646371 3.1.3.64 phosphatidylinositol-3-phosphatase fibroblast - 665599 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase fibroblast - 694495 3.1.3.67 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase fibroblast embryonic fibroblast 653630 3.1.3.95 phosphatidylinositol-3,5-bisphosphate 3-phosphatase fibroblast - 727365 3.1.4.1 phosphodiesterase I fibroblast dermal fibroblasts, PC-1 is either overexpressed or overactive in fibroblasts of insulin-resistant individuals both nondiabetic and diabetic 697620 3.1.4.1 phosphodiesterase I fibroblast tumor-derived and normal fibroblasts, patients with neurofibromatosis 208373 3.1.4.11 phosphoinositide phospholipase C fibroblast W-138 fibroblasts, expression of PLC delta isoenzymes 649088 3.1.4.12 sphingomyelin phosphodiesterase fibroblast - 135151, 135152, 135154, 135186, 664929, 678142 3.1.4.4 phospholipase D fibroblast - 664876, 666182, 707273, 707550, 707551 3.1.4.4 phospholipase D fibroblast dermal 707551 3.1.4.40 CMP-N-acylneuraminate phosphodiesterase fibroblast from skin of normal individuals and patients with salla disease 135469 3.1.4.41 sphingomyelin phosphodiesterase D fibroblast - 681248, 681249 3.1.5.B1 dNTPase fibroblast - 730819, 751048 3.1.6.12 N-acetylgalactosamine-4-sulfatase fibroblast - 707109, 708591 3.1.6.12 N-acetylgalactosamine-4-sulfatase fibroblast in culture 135563 3.1.6.13 iduronate-2-sulfatase fibroblast control 709970 3.1.6.14 N-acetylglucosamine-6-sulfatase fibroblast - 652758, 677855, 761256 3.1.6.15 N-sulfoglucosamine-3-sulfatase fibroblast - 95166 3.1.6.2 steryl-sulfatase fibroblast endometrial stromal fibroblast 751352 3.1.6.2 steryl-sulfatase fibroblast from normal and malignant breast tissue, study of the regulation of STS mRNA expression, expression in fibroblasts derived from breast tissue proximal to tumors, breast tumor tissue and reduction mammoplasty tissue, effect of menopausal status 656640 3.1.6.8 cerebroside-sulfatase fibroblast - 135691, 653357 3.10.1.1 N-sulfoglucosamine sulfohydrolase fibroblast - 288760 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase fibroblast - 680041 3.2.1.130 glycoprotein endo-alpha-1,2-mannosidase fibroblast - 646729 3.2.1.163 1,6-alpha-D-mannosidase fibroblast - 673892 3.2.1.18 exo-alpha-sialidase fibroblast - 171114, 171144 3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing) fibroblast - 721653 3.2.1.20 alpha-glucosidase fibroblast - 680016 3.2.1.207 mannosyl-oligosaccharide alpha-1,3-glucosidase fibroblast - 743909 3.2.1.21 beta-glucosidase fibroblast from healthy humans and Gaucher's disease patients 664628 3.2.1.22 alpha-galactosidase fibroblast - 678069 3.2.1.23 beta-galactosidase fibroblast - 697050, 703719 3.2.1.23 beta-galactosidase fibroblast confluency and contact inhibition of growth can cause a small increase in the expression. Senescent phenyotype is correlated with an increase in total beta-galactosidase 663624 3.2.1.23 beta-galactosidase fibroblast low activity during exponential growth phase, but increasing activity during decreasing culture growth and decreased mitotic activity 677571 3.2.1.23 beta-galactosidase fibroblast of GM1 gangliosidosis heterozygotes compared to normal subjects 655241 3.2.1.24 alpha-mannosidase fibroblast - 750617 3.2.1.25 beta-mannosidase fibroblast - 136046 3.2.1.33 amylo-alpha-1,6-glucosidase fibroblast from skin biopsies 171373 3.2.1.45 glucosylceramidase fibroblast - 656211, 663458, 663835, 663966, 665216, 678095, 679748, 680835, 682510, 682548, 702852, 703719, 703964, 749459, 750910, 751287, 751780, 752178 3.2.1.45 glucosylceramidase fibroblast normal fibroblasts and fibroblasts of patients with Gaucher disease 656804 3.2.1.45 glucosylceramidase fibroblast skin fibroblasts in culture 136453, 136461, 136470, 136473, 136474, 136479, 136484, 136487 3.2.1.45 glucosylceramidase fibroblast wild-type 715298 3.2.1.46 galactosylceramidase fibroblast - 697390 3.2.1.46 galactosylceramidase fibroblast from patients bearing nonsense mutations 751373 3.2.1.49 alpha-N-acetylgalactosaminidase fibroblast - 208653 3.2.1.49 alpha-N-acetylgalactosaminidase fibroblast from a patient with Fabry disease 707033 3.2.1.49 alpha-N-acetylgalactosaminidase fibroblast low levels, embryonic lung and gingival 655748 3.2.1.50 alpha-N-acetylglucosaminidase fibroblast - 697417 3.2.1.52 beta-N-acetylhexosaminidase fibroblast - 393690, 751281 3.2.1.52 beta-N-acetylhexosaminidase fibroblast skin fibroblast 393689 3.2.1.62 glycosylceramidase fibroblast - 680835 3.2.1.76 L-iduronidase fibroblast - 171551, 171553, 171554, 171559, 171562, 171569, 665552, 732511 3.2.2.19 [protein ADP-ribosylarginine] hydrolase fibroblast - 137044 3.2.2.23 DNA-formamidopyrimidine glycosylase fibroblast - 682052 3.2.2.29 thymine-DNA glycosylase fibroblast - 750696 3.3.2.6 leukotriene-A4 hydrolase fibroblast - 647020, 752495 3.4.11.1 leucyl aminopeptidase fibroblast - 95187 3.4.11.18 methionyl aminopeptidase fibroblast - 677503 3.4.11.2 membrane alanyl aminopeptidase fibroblast - 666240, 666997 3.4.11.2 membrane alanyl aminopeptidase fibroblast gingival 666148 3.4.11.2 membrane alanyl aminopeptidase fibroblast lung 666998 3.4.11.2 membrane alanyl aminopeptidase fibroblast nonstimulated from healthy skin, expression analysis, 100% expression of CD13, high density expression on the cell surface 665146 3.4.11.2 membrane alanyl aminopeptidase fibroblast surrounding a lung tumor nest 666532 3.4.11.22 aminopeptidase I fibroblast - 666422, 666760 3.4.11.4 tripeptide aminopeptidase fibroblast - 682590 3.4.11.6 aminopeptidase B fibroblast cardiac, ventricular 664535 3.4.13.19 membrane dipeptidase fibroblast isolated from skin 753783 3.4.13.9 Xaa-Pro dipeptidase fibroblast - 667803, 683061, 683216, 683227, 683457, 683612, 708394 3.4.13.9 Xaa-Pro dipeptidase fibroblast derived from normal skin and teloid tissue 668109 3.4.13.9 Xaa-Pro dipeptidase fibroblast derived from skin 669703, 670488 3.4.14.10 tripeptidyl-peptidase II fibroblast - 682590, 707371 3.4.14.5 dipeptidyl-peptidase IV fibroblast - 36225, 695876, 703784 3.4.14.5 dipeptidyl-peptidase IV fibroblast fibroblasts from patients with Fabry disease and a healthy person 704968 3.4.14.5 dipeptidyl-peptidase IV fibroblast lung-derived and skin-derived 709456 3.4.14.5 dipeptidyl-peptidase IV fibroblast normal, 3T3, and transformed, 3T12 36209 3.4.14.9 tripeptidyl-peptidase I fibroblast - 664560 3.4.15.1 peptidyl-dipeptidase A fibroblast cultured, corneal 710024 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase fibroblast - 36268 3.4.16.2 lysosomal Pro-Xaa carboxypeptidase fibroblast foreskin fibroblast 36269 3.4.16.5 carboxypeptidase C fibroblast - 677595, 702451, 704549 3.4.17.12 carboxypeptidase M fibroblast very low activity 697395 3.4.17.23 angiotensin-converting enzyme 2 fibroblast cardiac fibroblast 762787 3.4.17.23 angiotensin-converting enzyme 2 fibroblast primary kidney fibroblast 762703 3.4.17.23 angiotensin-converting enzyme 2 fibroblast primary lung fibroblast 752512 3.4.17.3 lysine carboxypeptidase fibroblast foreskin 36393 3.4.19.12 ubiquitinyl hydrolase 1 fibroblast accumulated upon growth stimulation of starved human fibroblasts 646102 3.4.19.12 ubiquitinyl hydrolase 1 fibroblast embryonic 708338 3.4.19.12 ubiquitinyl hydrolase 1 fibroblast weakly expressed in fibroblasts during wound healing 752715 3.4.21.107 peptidase Do fibroblast - 653189, 717650 3.4.21.107 peptidase Do fibroblast synovial, main source of secreted enzyme 683641 3.4.21.108 HtrA2 peptidase fibroblast - 700912 3.4.21.112 site-1 protease fibroblast - 754362 3.4.21.26 prolyl oligopeptidase fibroblast - 683926 3.4.21.26 prolyl oligopeptidase fibroblast lung-derived and skin-derived 709456 3.4.21.34 plasma kallikrein fibroblast prekallikrein expression 653115 3.4.21.38 coagulation factor XIIa fibroblast - 709089 3.4.21.41 complement subcomponent C1r fibroblast - 81402 3.4.21.42 complement subcomponent C1s fibroblast dermal fibroblast 652063 3.4.21.42 complement subcomponent C1s fibroblast skin and synovial membrane 81402 3.4.21.46 complement factor D fibroblast - 752876 3.4.21.6 coagulation factor Xa fibroblast - 717234, 717829 3.4.21.68 t-Plasminogen activator fibroblast - 664747 3.4.21.68 t-Plasminogen activator fibroblast embryonic lung diploid cells, IMR-90 cells, ATCC, CCL186 29594 3.4.21.69 Protein C (activated) fibroblast rheumatoid synovial fibroblasts 732526 3.4.21.7 plasmin fibroblast - 709033 3.4.21.73 u-Plasminogen activator fibroblast - -, 29663, 707070, 707951, 710248 3.4.21.73 u-Plasminogen activator fibroblast lung 710553 3.4.21.75 Furin fibroblast - 670247 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast - -, 650283, 676253, 676269, 678329, 678473, 732455 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast activated stromal fibroblasts 731767 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast cancer-associated 753092 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast expressed by cancer-associated fibroblasts in the microenvironment of most solid tumors 752802 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast expressed in most stromal fibroblasts 753136 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast in foci but not in interstitium 673949 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast of epithelial cancer and foreskin fibroblasts grown to confluence and maintained in low-serum media for up to 10 days 650762 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast reactive stromal fibromlasts of breast, colorectal, lung and other epithelial cancers 651537 3.4.21.B28 fibroblast activation protein alpha subunit fibroblast reactive tumor stromal fibroblast and granulation tissue during wound healing 651968 3.4.21.B3 duodenase fibroblast from pulmonary artery 658604 3.4.21.B43 kallikrein 12 fibroblast - 731781 3.4.22.1 cathepsin B fibroblast - 669158, 708033, 709922 3.4.22.1 cathepsin B fibroblast embryonic 696540 3.4.22.1 cathepsin B fibroblast gingival 699130 3.4.22.1 cathepsin B fibroblast protease v-Src-transformed fibroblasts 697099 3.4.22.15 cathepsin L fibroblast - 681907, 713010 3.4.22.15 cathepsin L fibroblast secreted from fibroblasts in response to external stimuli 650415 3.4.22.36 caspase-1 fibroblast - 679075 3.4.22.38 cathepsin K fibroblast - -, 667486, 701180, 708450, 709307 3.4.22.38 cathepsin K fibroblast synovial 700549 3.4.22.38 cathepsin K fibroblast tumor, stromal myofibroblasts, high expression level 697375 3.4.22.40 bleomycin hydrolase fibroblast - 753233 3.4.22.49 separase fibroblast - 732703 3.4.22.52 calpain-1 fibroblast - 699654, 710561 3.4.22.53 calpain-2 fibroblast - 668497, 699654 3.4.22.53 calpain-2 fibroblast NR6 cell 644049 3.4.22.55 caspase-2 fibroblast - 688972 3.4.22.55 caspase-2 fibroblast caspase-2 is required for apoptosis induced by cytoskeletal disruption. Caspase-2 mediates apoptosis via Piddosome, Bid and Bax activation, and cytochrome c release 689290 3.4.22.55 caspase-2 fibroblast embryonic fibroblasts deficient for both Bax and Bak indicate the contribution of both Bax and Bak in mediating cell death induced by resveratrol and the existence of Bax/Bak-independent cell death possibly through caspase-8- or caspase-2-mediated mitochondria-independent downstream caspase processing 687509 3.4.22.56 caspase-3 fibroblast - 647611 3.4.22.56 caspase-3 fibroblast embryonic 699298, 700881 3.4.22.59 caspase-6 fibroblast keloid fioblasts show a decreased expression of apoptosis-related genes compared to scars 695896 3.4.22.61 caspase-8 fibroblast - 707575 3.4.22.61 caspase-8 fibroblast rheumatoid synovial 701196 3.4.22.62 caspase-9 fibroblast - 647419, 666513 3.4.22.62 caspase-9 fibroblast caspase-9 null mouse embryo fibroblast 698775 3.4.22.62 caspase-9 fibroblast embryonic 681912 3.4.22.B30 calpain 10 fibroblast in Capn10-/- mouse embryonic fibroblasts, MAP1B is localized at actin filaments rather than at microtubules 755499 3.4.22.B66 caspase-12 fibroblast - 718146 3.4.22.B70 SENP1 peptidase fibroblast - 713707 3.4.23.46 memapsin 2 fibroblast - 669344 3.4.23.46 memapsin 2 fibroblast immortalized mouse embryonic fibroblasts from wild-type, and presenilin-deficient PS1-/-, PS2-/-, PS1-/-/PS2-/- mice. Oxidative stress fails to induce BACE1 expression in presenilin-1 deficient cells 700411 3.4.23.5 cathepsin D fibroblast - 36930, 696402, 711668 3.4.23.5 cathepsin D fibroblast foreskin fibroblast 650788 3.4.24.11 neprilysin fibroblast - 735083, 81609, 81616 3.4.24.11 neprilysin fibroblast embryonic 669936 3.4.24.14 procollagen N-endopeptidase fibroblast - 668834, 753530, 754590, 754632 3.4.24.17 stromelysin 1 fibroblast cultured skin fibroblast. Induction of enzyme and matrix metalloproteinase MMP-1 expression by heat shock. Suppression of induction by the inhibition of extracellular signal-regulated kinase and c-Jun N-terminal kinase and by specific inhibition of interleukin IL-6 by monoclonal antibody 669747 3.4.24.17 stromelysin 1 fibroblast decidual 710257 3.4.24.17 stromelysin 1 fibroblast gingival, gingival fibroblasts produce MMP-3 in response to inflammatory cytokines, such as TNF and interleukin-1 709669 3.4.24.18 meprin A fibroblast - 735169 3.4.24.19 procollagen C-endopeptidase fibroblast - 668838 3.4.24.22 stromelysin 2 fibroblast - -, 708422, 734685 3.4.24.23 matrilysin fibroblast aortic and adventitial 709561 3.4.24.23 matrilysin fibroblast gingival 709669 3.4.24.23 matrilysin fibroblast stromal 683945 3.4.24.24 gelatinase A fibroblast - 712141, 717633 3.4.24.24 gelatinase A fibroblast cardiac 683045 3.4.24.24 gelatinase A fibroblast from periodontal ligaments 733040 3.4.24.24 gelatinase A fibroblast GelA is expressed in fibroblasts surrounding apoptotic cells of intestine and tail 668208 3.4.24.24 gelatinase A fibroblast primary dermal 683466 3.4.24.35 gelatinase B fibroblast - 699032, 699716, 700406, 708690, 709572, 717454 3.4.24.63 meprin B fibroblast - 735169 3.4.24.63 meprin B fibroblast enzyme expression 734610 3.4.24.7 interstitial collagenase fibroblast - 655414, 656898, 683988, 699874, 708511, 708788, 709025, 709482, 717074, 733225, 733743, 734377, 754756, 755250, 95818, 95824, 95829, 95833, 95834 3.4.24.7 interstitial collagenase fibroblast dermal 668666, 707313 3.4.24.7 interstitial collagenase fibroblast dermal fibroblast 733049 3.4.24.7 interstitial collagenase fibroblast dermal, primary 707397 3.4.24.7 interstitial collagenase fibroblast dermal, quantitative MMP-1 expression analysis by RT-PCR 683451 3.4.24.7 interstitial collagenase fibroblast expression of MMP-1 is markedly increased by both onion extract and quercetin in vitro in human skin fibroblasts 717678 3.4.24.7 interstitial collagenase fibroblast expression of MMP-1 is markedly increased by both onion extract and quercetin in vivo in hairless mice 717678 3.4.24.7 interstitial collagenase fibroblast fibroblasts 95823, 95825, 95832 3.4.24.7 interstitial collagenase fibroblast from lung 683633 3.4.24.7 interstitial collagenase fibroblast gingival 665844 3.4.24.7 interstitial collagenase fibroblast gingival, gingival fibroblasts produce MMP-1 in response to inflammatory cytokines, such as TNF and interleukin-1 709669 3.4.24.7 interstitial collagenase fibroblast healthy dermal fibroblasts and cultured Xeroderma pigmentosum-C fibroblasts, increased MMP1 expression in cultured XP-C fibroblasts results from MMP1 mRNA accumulation and enhanced transcriptional activity of the MMP1 gene promoter, overview 682206 3.4.24.7 interstitial collagenase fibroblast NHDFs and NB1RGBs 683221 3.4.24.7 interstitial collagenase fibroblast overexpression of phospholipid-hydroperoxide glutathione peroxidase in human dermal fibroblasts abrogates UVA irradiation-induced expression of interstitial collagenase/matrix metalloproteinase-1 by suppression of phosphatidylcholine hydroperoxide-mediated NFkappaB activation and interleukin-6 release 669276 3.4.24.7 interstitial collagenase fibroblast primary cultured corneal and tenon's fibroblast 667138 3.4.24.7 interstitial collagenase fibroblast primary human neonatal dermal fibroblasts 754720 3.4.24.7 interstitial collagenase fibroblast primary lung fibroblast cell lines 683445 3.4.24.7 interstitial collagenase fibroblast production of MMP-1 by keloid fibroblasts is 6fold greater than that of normal dermal fibroblasts. The production of MMP-1 is decreased by addition of TGF-beta1 to cultured keloid fibroblasts, while it is increased when anti-TGF-beta1 antibody is added to the culture 668108 3.4.24.7 interstitial collagenase fibroblast synovial fibroblast 709789 3.4.24.79 pappalysin-1 fibroblast - 638932, 638933, 638935, 638937, 683504 3.4.24.80 membrane-type matrix metalloproteinase-1 fibroblast - 638803, 638810, 678111, 680268, 681831, 754158, 95837 3.4.24.80 membrane-type matrix metalloproteinase-1 fibroblast aortic fibroblasts 754508 3.4.24.80 membrane-type matrix metalloproteinase-1 fibroblast isolated from the dermis of late gestation embryos in mice deficient in MT1-MMP 683300 3.4.24.80 membrane-type matrix metalloproteinase-1 fibroblast neonatal cardiac myofibroblasts 683787 3.4.24.81 ADAM10 endopeptidase fibroblast - 668407, 669333, 669480, 670247, 670688, 709068 3.4.24.81 ADAM10 endopeptidase fibroblast ADAM17-/-, Ras-Myc-immortalized murine fibroblasts. ADAM10 is a major TNF sheddase in ADAM17-deficient fibroblasts 708269 3.4.24.82 ADAMTS-4 endopeptidase fibroblast - 667400 3.4.24.84 Ste24 endopeptidase fibroblast - 670378 3.4.24.86 ADAM 17 endopeptidase fibroblast - -, 638979, 638988, 638991, 638992, 638995, 639001, 639003, 639004, 639006, 639011, 639012, 669269, 669572, 711143 3.4.24.86 ADAM 17 endopeptidase fibroblast dermal fibroblasts 638996 3.4.24.86 ADAM 17 endopeptidase fibroblast embryonic fibroblast 713063, 735270 3.4.24.B10 ADAM12 endopeptidase fibroblast - 712445 3.4.24.B11 ADAMTS1 endopeptidase fibroblast - 669350 3.4.24.B18 m-AAA protease fibroblast embryonic fibroblast 752423 3.4.24.B19 i-AAA protease fibroblast - 753424 3.4.24.B3 matrix metalloproteinase-11 fibroblast - 669363, 682261 3.4.24.B3 matrix metalloproteinase-11 fibroblast MMP-11 stimulation in mouse fibroblasts using cytokines, matrix constituents and HBC cell lines 668082 3.4.24.B4 matrix metalloproteinase-13 fibroblast - 650906, 711041, 711684 3.4.24.B4 matrix metalloproteinase-13 fibroblast expression by fibroblasts inadult gingival and in fetal skin wounds characterized by rapid collagen remodeling and scarless healing 669755 3.4.24.B4 matrix metalloproteinase-13 fibroblast rheumatoid synovial fibroblast 668235 3.4.24.B7 matrix metalloproteinase-26 fibroblast - 686591 3.4.25.1 proteasome endopeptidase complex fibroblast lung 651219 3.4.99.B1 RCE1 fibroblast - 754117 3.5.1.12 biotinidase fibroblast - 171919, 171924, 171935, 670277 3.5.1.15 aspartoacylase fibroblast - 209008 3.5.1.23 ceramidase fibroblast - 669485, 734696, 753570 3.5.1.23 ceramidase fibroblast alkaline ceramidase 719197 3.5.1.52 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase fibroblast C3H mouse-derived L-929 fibroblast cells 288922, 288927 3.5.1.92 pantetheine hydrolase fibroblast primary -, 757352 3.5.1.98 histone deacetylase fibroblast - 678443 3.5.2.9 5-oxoprolinase (ATP-hydrolysing) fibroblast - 209384 3.5.4.12 dCMP deaminase fibroblast the enzyme activity is higher in normal Rat-2 fibroblast compared to transformed NM-16 cells 667541 3.5.4.38 single-stranded DNA cytosine deaminase fibroblast - 755553 3.5.4.4 adenosine deaminase fibroblast reduced enzyme activity is associated with increased membrane fluidity in transformed versus normal fibroblasts 654832 3.6.1.1 inorganic diphosphatase fibroblast cell culture 209791 3.6.1.42 guanosine-diphosphatase fibroblast - 210055 3.6.1.5 apyrase fibroblast - -, 718543 3.6.1.5 apyrase fibroblast portal fibroblasts -, 718543 3.6.1.52 diphosphoinositol-polyphosphate diphosphatase fibroblast - 668226 3.6.1.6 nucleoside diphosphate phosphatase fibroblast - 718543 3.6.1.62 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] hydrolase fibroblast embryonic fibroblast 734680 3.6.1.7 acylphosphatase fibroblast increased levels of ACYP have been revealed in fibroblasts from patients affected by Alzheimer's disease 758508 3.6.1.71 adenosine-5'-diphospho-5'-[DNA] diphosphatase fibroblast - 741072, 750390, 750720 3.6.1.9 nucleotide diphosphatase fibroblast - 756660 3.6.4.10 non-chaperonin molecular chaperone ATPase fibroblast fibroblast cell line EHS from the tail fin, heat-shock cognate protein 70 668719 3.6.4.10 non-chaperonin molecular chaperone ATPase fibroblast fibroblast cell line EHS from the tail fin, heat-shock protein 70 668719 3.6.4.10 non-chaperonin molecular chaperone ATPase fibroblast overexpression of mortalin/mtHsp70 extends the in vitro lifespan of normal human fibroblasts 667512 3.6.4.13 RNA helicase fibroblast - 756594 3.6.4.13 RNA helicase fibroblast fetal lung fibroblasts 757299 3.6.4.6 vesicle-fusing ATPase fibroblast from PBD patients 210581, 210583 3.6.4.7 peroxisome-assembly ATPase fibroblast - 210588, 210589, 210590, 685048 3.6.5.2 small monomeric GTPase fibroblast - 644125, 644135, 688916 3.7.1.2 fumarylacetoacetase fibroblast - 289252 4.1.1.17 ornithine decarboxylase fibroblast - 680257, 696087, 698358 4.1.1.17 ornithine decarboxylase fibroblast neonatal foreskin fibroblasts 681869 4.1.1.33 diphosphomevalonate decarboxylase fibroblast - 653248 4.1.1.50 adenosylmethionine decarboxylase fibroblast - 704069, 715193 4.1.1.84 D-dopachrome decarboxylase fibroblast murine embryonic fibroblast 693465 4.1.1.90 peptidyl-glutamate 4-carboxylase fibroblast - 695615 4.1.2.27 sphinganine-1-phosphate aldolase fibroblast - 5119, 747522 4.1.2.27 sphinganine-1-phosphate aldolase fibroblast embryonic fibroblast 708071 4.1.2.27 sphinganine-1-phosphate aldolase fibroblast skin 5120 4.1.2.4 deoxyribose-phosphate aldolase fibroblast - 5181 4.1.3.4 hydroxymethylglutaryl-CoA lyase fibroblast - 652427, 681959 4.1.3.4 hydroxymethylglutaryl-CoA lyase fibroblast skin, cultured 5374 4.1.99.13 (6-4)DNA photolyase fibroblast - 682264, 692022 4.2.1.17 enoyl-CoA hydratase fibroblast - 748661 4.2.1.18 methylglutaconyl-CoA hydratase fibroblast - 33741 4.2.1.18 methylglutaconyl-CoA hydratase fibroblast activity of 3-methylglutaconyl-CoA hydratase measured 681226 4.2.1.18 methylglutaconyl-CoA hydratase fibroblast direct activity assay in fibroblast homogenates 679737 4.2.1.18 methylglutaconyl-CoA hydratase fibroblast skin 716241 4.2.1.2 fumarate hydratase fibroblast - 696399 4.2.1.22 cystathionine beta-synthase fibroblast - 650105, 650408, 652551, 697850 4.2.1.3 aconitate hydratase fibroblast - 696992 4.2.1.3 aconitate hydratase fibroblast B6 651975 4.2.3.12 6-pyruvoyltetrahydropterin synthase fibroblast cells from patients with BH4 deficiency 648563 4.2.3.134 5-phosphonooxy-L-lysine phospho-lyase fibroblast - 730145 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase fibroblast - 648657, 679468 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase fibroblast embryonic 664729 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase fibroblast GM00637 666500 4.2.99.18 DNA-(apurinic or apyrimidinic site) lyase fibroblast SV40-transformed human skin fibroblasts, CS1AN.S3.G2 682176 4.3.2.1 argininosuccinate lyase fibroblast - 730448 4.3.2.2 adenylosuccinate lyase fibroblast - 710076, 729218 4.6.1.1 adenylate cyclase fibroblast - 695078 4.6.1.1 adenylate cyclase fibroblast embryo 34776 4.6.1.1 adenylate cyclase fibroblast neonatal cardiac, isozyme AC2 is localized to the same structures in adult mice 691717 4.6.1.1 adenylate cyclase fibroblast neonatal cardiac, isozyme AC5 is localized to the same structures in adult mice 691717 4.6.1.1 adenylate cyclase fibroblast normal and Rous sarcoma transformed 34776 4.98.1.1 protoporphyrin ferrochelatase fibroblast cultured 34970 5.1.3.14 UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) fibroblast skin 2275 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase fibroblast embryonic -, 704486, 704951 5.1.3.19 chondroitin-glucuronate 5-epimerase fibroblast - 727608 5.1.3.19 chondroitin-glucuronate 5-epimerase fibroblast 30-50% decreased activity in fibroblasts treated with high xyloside concentrations 2303 5.1.3.19 chondroitin-glucuronate 5-epimerase fibroblast embryonic 2299, 2304 5.1.3.19 chondroitin-glucuronate 5-epimerase fibroblast skin 2291, 2299, 2300, 2302, 2303, 2304 5.1.99.4 alpha-methylacyl-CoA racemase fibroblast - 2447 5.1.99.6 NAD(P)H-hydrate epimerase fibroblast - 746703 5.2.1.2 maleylacetoacetate isomerase fibroblast GSTzeta/MAAI is induced during the differentiation of 3T3-L1 fibroblasts into adipocytes. This process requires expression of C/EBPalpha as well as PPARgamma 660927 5.2.1.8 peptidylprolyl isomerase fibroblast - 703024, 705427, 746479, 746973 5.2.1.8 peptidylprolyl isomerase fibroblast embryonic fibroblast,comparative analysis of enzyme activities and mRNA level of Pin1 and other prolyl cis/trans isomerases 679822 5.3.3.12 L-dopachrome isomerase fibroblast - 648806 5.3.3.2 isopentenyl-diphosphate DELTA-isomerase fibroblast in normal fibroblasts and Zellweger fibroblasts, in which the synthesis of cholesterol is impaired 2959 5.3.4.1 protein disulfide-isomerase fibroblast cultured, confluent 439186 5.3.4.1 protein disulfide-isomerase fibroblast lung 3076, 439186 5.3.99.2 Prostaglandin-D synthase fibroblast - 705307 5.3.99.3 prostaglandin-E synthase fibroblast 3Y1 cell 660973 5.3.99.3 prostaglandin-E synthase fibroblast colocalized with cyclooxygenase-2 660677 5.3.99.3 prostaglandin-E synthase fibroblast gingival fibroblast 678444 5.3.99.3 prostaglandin-E synthase fibroblast pEJ-ras transformed 3132 5.3.99.5 thromboxane-A synthase fibroblast low activity 3183 5.4.2.3 phosphoacetylglucosamine mutase fibroblast - 728799 5.4.2.8 phosphomannomutase fibroblast - 705755, 715810, 749066 5.4.99.2 methylmalonyl-CoA mutase fibroblast - 747209 5.6.1.1 microtubule-severing ATPase fibroblast - 210534, 210536, 210538, 210539, 699690, 700089 5.6.1.1 microtubule-severing ATPase fibroblast RFL-6 cell 699690 5.6.1.1 microtubule-severing ATPase fibroblast RFL6 675542 5.6.1.3 plus-end-directed kinesin ATPase fibroblast - 210541, 210544, 210550 5.6.1.4 minus-end-directed kinesin ATPase fibroblast - 733397 5.6.1.7 chaperonin ATPase fibroblast overexpression of Hsp60 does not extend the in vitro lifespan of normal human fibroblasts 667512 5.6.1.8 myosin ATPase fibroblast dermal 671012 5.6.1.8 myosin ATPase fibroblast prepared from embryonal chicken hearts 700094 5.6.2.3 DNA 5'-3' helicase fibroblast derived from healthy domors and xeroderma pigmentosum patients 757149 6.1.1.10 methionine-tRNA ligase fibroblast of foreskin 652598 6.1.1.12 aspartate-tRNA ligase fibroblast - 676127 6.1.1.15 proline-tRNA ligase fibroblast - 745339 6.1.1.16 cysteine-tRNA ligase fibroblast - 745531 6.1.1.16 cysteine-tRNA ligase fibroblast cultured 194 6.1.1.16 cysteine-tRNA ligase fibroblast from patients with cystinosis 194 6.1.1.17 glutamate-tRNA ligase fibroblast - 745339 6.1.1.19 arginine-tRNA ligase fibroblast - 671204 6.2.1.1 acetate-CoA ligase fibroblast - 746321 6.2.1.15 arachidonate-CoA ligase fibroblast - 640 6.2.1.16 acetoacetate-CoA ligase fibroblast - 650 6.2.1.24 phytanate-CoA ligase fibroblast skin, cell culture 705 6.2.1.3 long-chain-fatty-acid-CoA ligase fibroblast - 727094 6.2.1.4 succinate-CoA ligase (GDP-forming) fibroblast - 693488, 728078, 745246, 745498 6.2.1.4 succinate-CoA ligase (GDP-forming) fibroblast primary 714342 6.2.1.5 succinate-CoA ligase (ADP-forming) fibroblast - 693488, 728078, 745498, 745783 6.2.1.5 succinate-CoA ligase (ADP-forming) fibroblast primary 714342 6.3.1.2 glutamine synthetase fibroblast fetal 690626 6.3.2.2 glutamate-cysteine ligase fibroblast - 662512 6.3.2.2 glutamate-cysteine ligase fibroblast dermal 650713 6.3.2.25 tubulin-tyrosine ligase fibroblast - 675003 6.3.2.3 glutathione synthase fibroblast - 692439 6.3.4.10 biotin-[propionyl-CoA-carboxylase (ATP-hydrolysing)] ligase fibroblast - 1392, 705293 6.3.4.15 biotin-[biotin carboxyl-carrier protein] ligase fibroblast - 691104, 705293 6.3.4.15 biotin-[biotin carboxyl-carrier protein] ligase fibroblast cultured 1446 6.3.4.16 carbamoyl-phosphate synthase (ammonia) fibroblast - 672441 6.3.4.3 formate-tetrahydrofolate ligase fibroblast - 662447 6.3.4.3 formate-tetrahydrofolate ligase fibroblast embryonic fibroblast cell line 712483 6.3.4.3 formate-tetrahydrofolate ligase fibroblast SF6 cell, immortalized fibroblast with disrupted gene encoding the trifunctional cytosolic DCS 662447 6.3.4.7 ribose-5-phosphate-ammonia ligase fibroblast wild-type and mutant cell line deficient in phosphoribosyldiphosphate amidotransferase and phosphoribosyldiphosphate aminotransferase activities with normal activity of ribose-5-phosphate aminotransferase activities 1617 6.4.1.1 pyruvate carboxylase fibroblast low activity 649667 6.4.1.2 acetyl-CoA carboxylase fibroblast - 716068 6.4.1.4 methylcrotonoyl-CoA carboxylase fibroblast - 662746, 662747 6.5.1.1 DNA ligase (ATP) fibroblast - 1928, 653386, 694437, 709934 7.1.1.9 cytochrome-c oxidase fibroblast - 691404, 692575, 742002 7.2.2.9 P-type Cu2+ transporter fibroblast - 668543, 696595, 710802 7.2.2.9 P-type Cu2+ transporter fibroblast fibroblasts from the female Menkes translocation patient show no detectable expression of the transcript, five additional fibroblast lines from unrelated Menkes patients show alterations in the expression of this gene 246908 7.2.2.9 P-type Cu2+ transporter fibroblast isolated from Menkes disease patients, transfection with ATP7A 685944 7.4.2.14 ABC-type antigen peptide transporter fibroblast - 762296 7.4.2.3 mitochondrial protein-transporting ATPase fibroblast TIG-1 cell, overexpression of mortalin extends the in vitro lifespan of the fibroblasts 667512 7.6.2.1 P-type phospholipid transporter fibroblast - 246839, 668247 7.6.2.4 ABC-type fatty-acyl-CoA transporter fibroblast - 689002 7.6.2.4 ABC-type fatty-acyl-CoA transporter fibroblast X-ALD fibroblast lacking ALDP 688498