3.4.21.27 A7r5 cell - 752439 3.4.21.27 blood - 36530, 36531, 36532, 707856, 718045, 731538 3.4.21.27 blood plasma - 652338, 669347, 669428, 693547, 695184, 707856, 709721, 709722, 710438, 710600, 717420, 717844, 718042, 753068 3.4.21.27 blood plasma from patients with aortic stenosis 717416 3.4.21.27 blood platelet - 691466, 753068 3.4.21.27 blood vessel - 752615 3.4.21.27 brain - 36541 3.4.21.27 commercial preparation - 683682 3.4.21.27 commercial preparation from plasma 683160, 683167 3.4.21.27 kidney - 709722 3.4.21.27 leukocyte - 717958 3.4.21.27 liver - 707308, 709722 3.4.21.27 additional information hemophilia C (deficiency in FXI) is present in both sexes 707308 3.4.21.27 additional information the enzyme binds to platelets, a conformational transition accompanies conversion of factor XI to factor XIa that conceals the Apple 3 domain zymogen factor XI platelet binding site and exposes the factor XIa platelet binding site within the catalytic domain possibly comprising residues Cys527-Cys542, overview 683160 3.4.21.27 pancreas - 709722 3.4.21.27 plasma - 683157, 683160, 683167, 683682, 683756, 684078, 691011 3.4.21.27 umbilical vein endothelial cell line - 652309 3.4.21.27 vascular smooth muscle cell - 752439