3.1.1.98 blastoderm expression of Notum1a first appears around the blastoderm margin prior to the onset of gastrulation 733700 3.1.1.98 brain - 750384 3.1.1.98 central nervous system at 24 h post fertilization, expression is particularly pronounced in the central nervous system, including the dorsal neural tube and the midbrain-hindbrain boundary 733700 3.1.1.98 embryo - 733700 3.1.1.98 embryo Notum is expressed dynamically during Xenopus embryogenesis, expression is required for head formation and neural induction. Notum functions in the prostective ectoderm 733696 3.1.1.98 neural plate Notum1a is expressed in the lateral edges and midline of the posterior neural plate. During segmentation, it is expressed in stripes at the lateral edges and adjacent to the midline of the neural plate 733700 3.1.1.98 SW-620 cell - 749473