2.3.1.B43 16-HBE14o cell - 755970 2.3.1.B43 A-549 cell - 738009, 755970 2.3.1.B43 adipose tissue - -, 755970, 756563 2.3.1.B43 bladder - 755970 2.3.1.B43 blood - 755970 2.3.1.B43 bone - 755970 2.3.1.B43 brain - 739069, 755970, 756522 2.3.1.B43 breast cancer cell - 758247 2.3.1.B43 brown adipocyte - 756555 2.3.1.B43 cerebellar cortex in the cerebellar cortex, SIRT5 can be found in Purkinje cells, and is mainly distributed in the cytoplasm, but is not markedly expressed in the molecular layer or granular layer cells 730103 2.3.1.B43 cerebellar Purkinje cell - 730103 2.3.1.B43 connective tissue - 755970 2.3.1.B43 embryo - 755970 2.3.1.B43 embryonic fibroblast - 756522 2.3.1.B43 esophagus - 755970 2.3.1.B43 eye - 755970 2.3.1.B43 H9c2 cell - 729556 2.3.1.B43 heart - 739069, 755970, 756522, 757184 2.3.1.B43 HEK-293 cell - 757175 2.3.1.B43 HEK-293T cell - 755970 2.3.1.B43 HeLa cell - 755970 2.3.1.B43 Hep-G2 cell - 755970 2.3.1.B43 hepatocyte - 739069, 756522 2.3.1.B43 HHL-5 cell - 755970 2.3.1.B43 HL-7702 cell - 755970 2.3.1.B43 hypophysis - 755970 2.3.1.B43 intestine - 755970 2.3.1.B43 K-562 cell - 755970 2.3.1.B43 kidney - 739069, 755970, 756522 2.3.1.B43 liver - -, 728932, 729732, 755970, 756563, 757084 2.3.1.B43 liver SIRT5 expression is observed to localize strictly to the periportal hepatocytes 757175 2.3.1.B43 lung - 739069, 755970, 757084 2.3.1.B43 lung epithelial cell - 738009 2.3.1.B43 lymph node - 755970 2.3.1.B43 macrophage SIRT5 and SIRT1/2 have opposite expression patterns and functions in macrophages, overview 757084 2.3.1.B43 mammary gland - 755970 2.3.1.B43 MDA-MB-231 cell - 758247 2.3.1.B43 MEF cell - 738110 2.3.1.B43 additional information SIRT5 displays broad tissue distribution, with highest levels in brain, heart, liver, kidney, muscle, and testis 756522 2.3.1.B43 additional information sirtuin 5 (SIRT5) is upregulated in patients with type 2 diabetes and in pancreatic beta cell lines 756680 2.3.1.B43 additional information the SIRT5 gene is widely expressed, but expression patterns of different isoforms vary in tissues, expression analysis, overview 755970 2.3.1.B43 mouth - 755970 2.3.1.B43 muscle - 756522 2.3.1.B43 NCI-H1299 cell - 755970 2.3.1.B43 neuron predominantly nuclear 730103 2.3.1.B43 neuron SIRT5 isozyme 2 755970 2.3.1.B43 non-small cell lung cancer cell SIRT5 is overexpressed in human non-small cell lung cancer cells, high expression of SIRT5 predicts poor survival 731010 2.3.1.B43 pancreas - 739069, 755970, 756680 2.3.1.B43 pancreatic beta cell - 756680 2.3.1.B43 placenta - 755970 2.3.1.B43 prostate gland - 755970 2.3.1.B43 skeletal muscle - -, 756563 2.3.1.B43 skin - 755970 2.3.1.B43 stomach - 755970 2.3.1.B43 testis - 755970, 756522 2.3.1.B43 thymus - 755970 2.3.1.B43 thyroid gland - 755970 2.3.1.B43 trachea - 755970 2.3.1.B43 uterine cervix - 755970 2.3.1.B43 uterus - 755970 2.3.1.B43 white adipocyte - 756555