1.1.1.79 cell suspension culture - 722899 1.1.1.79 epithelium - 739242 1.1.1.79 fruit - 761177 1.1.1.79 glume - 760794 1.1.1.79 HEP-3B cell - 739241 1.1.1.79 Hep-G2 cell - 739241 1.1.1.79 hepatocellular carcinoma cell enzyme GRHPR is lost in hepatocellular carcinoma (HCC) and proliferative HCC cells 739241 1.1.1.79 HL-7702 cell - 739241 1.1.1.79 HT-29 cell - 739242 1.1.1.79 HT-29 cell cultured with tumor necrosis factor alpha 739242 1.1.1.79 Huh-7 cell GRHPR is reduced in proliferative Huh7 cells 739241 1.1.1.79 intestinal epithelial cell - 739242 1.1.1.79 intestine - 739242 1.1.1.79 leaf - 287318, 287320, 287329, 688090, 688091, 722899, 760794, 761177 1.1.1.79 leaf sheath - 760794 1.1.1.79 liver - 669351, 669886, 739242 1.1.1.79 liver the enzyme plays a critical role in the removal of the metabolic by-product glyoxylate from within the liver. Deficiency of this enzyme is the underlying cause of primary hyperoxaluria type 2 (PH2) and leads to increased urinary oxalate levels, formation of kidney stones and renal failure 669886 1.1.1.79 additional information immunohistochemic tissue expression analysis of GRHPR, overview. GRHPR shows a lower expression in tumor tissues than in nontumoral tissues. GRHPR is negatively correlated with Ki-67 739241 1.1.1.79 seedling - 722899 1.1.1.79 SMMC-7721 cell - 739241 1.1.1.79 xylem - 287326