4.2.1.56	metabolism	the enzyme is involved in the catabolic pathway of itaconic acid	-, 746855	
4.2.1.56	metabolism	the enzyme is involved in the degradation of itaconate. Itaconyl-CoA hydratase reaction as a bottleneck in the conversion. Its activity is an order of magnitude lower than the activities of itaconate-CoA transferase and (S)-citramalyl-CoA lyase	-, 746828