3.6.1.27	malfunction	an undecaprenyl pyrophosphate phosphatase null mutant does not show any significant growth or morphological defect, neither is its sensitivity to bacitracin affected. However, the enzyme activity in the mutant is reduced by 75%	718534	
3.6.1.27	malfunction	enzyme deletion results in a mutant with reduced biofilm formation that is highly sensitive to bacitracin, but confers more resistance to lactococcin G	-, 757618	
3.6.1.27	malfunction	enzyme depletion disrupts cell envelope biogenesis in Bacillus subtilis and leads to morphological defects consistent with a failure of cell envelope synthesis and strongly activates the sigmaM-dependent cell envelope stress response	757099	
3.6.1.27	malfunction	single uppP or bcrC enzyme deletions show no or less than 0.1% misshaped cells. In contrast, both enzyme depletions leads to a severe phenotype during exponential growth phase	756791	
3.6.1.27	physiological function	mutants lacking enzymic activity show no significant changes in growth rate, colony morphology and biofilm formation. The mutants exhibit increased susceptibility to bacitracin. When the enzyme is expressed in a wild-type background, the minimum inhibitory concentration of bacitracin increases to 256 mg/L. The minimum inhibitory concentrations of cefoxitin, teicoplanin, vancomycin, gentamicin, enrofloxacin and D-cycloserine are unaltered in the mutant relative to the wild-type, as are susceptibilities to other stress agents such as glycine, lysozyme, NaCl, SDS, low and high pH, oxidative stress and ethanol	734038	
3.6.1.27	physiological function	the enzyme BcrC is more relevant during vegetative growth while the enzyme UppP is crucial for normal sporulation. Together, enzyme forms bcrC and uppP encode the essential undecaprenyl diphosphatase function of Bacillus subtilis	756791	
3.6.1.27	physiological function	the enzyme confers resistance to bacitracin	718534	
3.6.1.27	physiological function	the enzyme is essential in vivo for stomach colonization and is also involved in cationic antimicrobial peptide resistance	-, 758199	
3.6.1.27	physiological function	the enzyme plays important roles in cell wall biosynthesis and bacitracin resistance	-, 757618