3.5.1.105	evolution	chitin deacetylases and chitooligosaccharides deacetylases [EC 3.5.1.105 (CODa)]. ChDas and CODa are a group of enzymes catalyzing the hydrolysis of acetamido groups of N-acetyl-D-glucosamine residues in chitin, chitosan and chitooligosaccharides, respectively. Both of these groups of enzymes are classified in the carbohydrate esterase family 4 (CE4) in the CAZY database	-, 753650	
3.5.1.105	evolution	chitin oligosaccharide deacetylase (COD) typically comprise two carbohydrate-binding domains (CBDs) and one polysaccharide deacetylase domain. In contrast, Shewanella baltica ATCC BAA-1091 COD (Sb-COD) has only one CBD, yet exhibits chitin-binding properties and substrate specificities similar to those of other CODs	-, 753032	
3.5.1.105	evolution	the enzyme belongs to carbohydrate esterase (CE) family 14	-, 745652	
3.5.1.105	evolution	the enzyme belongs to the carbohydrate esterase family 14	-, 752555	
3.5.1.105	evolution	the enzyme belongs to the carbohydrate esterase family 4. Amino acid residues that officiate as the metal ion-binding triad and general acid–base catalysts are generally conserved in other Zn-dependent deacetylases	-, 733875	
3.5.1.105	evolution	the enzyme is an evolutionarily conserved protein that belongs to the the YdjC family of proteins	-, 734074	
3.5.1.105	evolution	YDJC belongs to the YDJC superfamily and exerts deacetylase activity	754966	
3.5.1.105	malfunction	gene silencing of YDJC suppresses sphingosylphosphorylcholine (SPC)-induced events. YdjC overexpression induces the SPC-induced events. YdjC deacetylase dominant negative mutant (YDJCD13A) does not induce SPC-induced events. YDJC siRNA reduces ERK activation and overexpression of YDJC induces ERK activation. The siRNA of ERK1 or ERK2 suppresses YDJC-induced phosphorylation and reorganization of keratin 8 (K8), and migration and invasion	754966	
3.5.1.105	metabolism	deacetylated chitobiose and chitotriose provide the induction signal necessary for the activation of the ChbR regulator	-, 734074	
3.5.1.105	metabolism	diacetylchitobiose deacetylase works in the chitin degradation pathway in combination with glucosaminidase to hydrolyze diacetylchitobiose (GlcNAc2) to glucosamine (GlcN). First, the N-acetyl group of GlcNAc2 is catalyzed by Dac from the nonreducing end residue N-acetylglucosamine (GlcNAc) of GlcNAc2 and generates the product GlcN-GlcNAc, the product (GlcNGlcNAc) is then hydrolyzed by glucosaminidase following degradation into GlcN and GlcNAc. Finally, the resulting monomer GlcNAc is catalyzed by Dac to generate GlcN	-, 752555