3.4.24.73	additional information	jararhagin toxin binding to collagen appears to be sufficient to inhibit collagen-induced platelet aggregation in the human host	710633	
3.4.24.73	physiological function	jararhagin 0.03 mg/ml upregulated genes TP53, CDKN1A, CDKN2A, CASP3, CASP5, CASP6, CASP8, and E-CDH in SKMel-28, and genes ITGB6, ITGB7, CASP3, TP53, and CDKN1B in mouse fibroblasts	721080	
3.4.24.73	physiological function	jararhagin induces strong hemorrhage accompanied by hydrolysis of collagen fibers in the hypodermis and a marked degradation of type IV collagen at the vascular basement membrane. Toxin accumulation near blood vessels leads to enhanced catalysis of basement membrane components, resulting in the strong hemorrhagic activity of jararhagin	720805