3.2.2.24 physiological function DraG is a key player in the regulation of nitrogenase activity. The enzyme, catalyzing removal of the ADP-ribose moiety, is involved in the reversible ADP-ribosylation, a ubiquitous regulatory posttranslational modification involved in numerous key processes such as DNA repair, transcription, cell differentiation, apoptosis, and the pathogenic mechanism of certain bacterial toxins 710412 3.2.2.24 physiological function protein-reversible ADP-ribosylation is an important posttranslational modification used to control enzymatic and protein activity in different biological systems. This modification regulates nitrogenase activity in several nitrogen-fixing bacterial species. ADP-ribosylation is catalyzed by ADP-ribosyltransferases and is reversed by ADP-ribosylhydrolases 709521