3.1.3.9 malfunction enzyme loss reduces glucose uptake, intracellular ATP, and endoplasmic reticulum Ca2+ content 750367 3.1.3.9 malfunction expression of hepatic glucose-6-phosphatase-alpha is down-regulated in patients with hepatic steatosis 716402 3.1.3.9 malfunction G6PC3 mutation induces major alterations in neutrophil N- and O-glycomes 715135 3.1.3.9 malfunction glycogen storage disease type Ia characterized by impaired glucose homeostasis and chronic risk of hepatocellular adenoma, is caused by a deficiency in glucose-6-phosphatase-alpha activity 751577 3.1.3.9 metabolism an enhanced glucose 6-phosphatase activity in liver of rats exposed to Mg2+-deficient diet is detected 713961 3.1.3.9 physiological function the enzyme is required for glucose uptake, ATP production, and Ca2+ uptake by the endoplasmic reticulum 750367