3.1.1.59	malfunction	silencing of the enzyme affects expression of the other developmental genes without a specific phenotype, e.g. mRNA accumulation of heat shock protein 70, SnHsp70, is increased while the heat shock cognate 70, SnHsc70, and ecdysone receptor, SnEcR, mRNA accumulation is decreased	730748	
3.1.1.59	malfunction	upon RNAi-mediated silencing of the methyl farnesoate epoxidase gene mfe encoding the enzyme that catalyzes methyl farnesoate-to-juvenile hormone conversion, the juvenile hormone titer is decreased, juvenile hormone titer regulation in adult honey bees depends on this final juvenile hormone biosynthesis step, overview	730778	
3.1.1.59	physiological function	ab1A olfactory neurons of jhedup mutant flies exhibit an increased response to certain food acetates. Mutant flies show a higher sensitivity towards the same odorants in behavioural assays	752213	
3.1.1.59	physiological function	Bmcce-5 is strongly expressed in Malpighian tubules and the gut, it might function in digestion or xenobiotic metabolism	715173	
3.1.1.59	physiological function	BmJHE, a juvenile hormone-selective esterase, JHE, is important for juvenile hormone titer regulation in the silkworm Bombyx mori	715173	
3.1.1.59	physiological function	JHE is the enzyme primarily performing juvenile hormone degradation in Apis mellifera, while the JH epoxide hydrolase, EC 3.3.2.9, plays a negligible role	715819	
3.1.1.59	physiological function	JHEs are required for the degradation of juvenile hormones in insects	715184	
3.1.1.59	physiological function	juvenile hormone controls key events in the honey bee life cycle, the juvenile hormone-degrading enzyme is of importance in regulating larval juvenile hormone titers and caste development, as well as age polyethism, expression of 24 genes involved in the juvenile hormone biosynthetic pathway in the corpora allata-corpora cardiaca, overview	730778	
3.1.1.59	physiological function	knockdown of expression by RNAi reduces juvenile hormone esterase activity and interrupts pupal development with a significant increase of larval period	751264	
3.1.1.59	physiological function	penultimate (4th) instar larvae infected with nucleopolyhedroviruses AdhoNPV or AdorNPV show a marked decrease in JHE activity. The mean survival time is 9.7 and 8.2 days, respectively. The larvae molt once but do not pupate	751263