2.8.1.9 metabolism molybdenum cofactor biosynthesis 390372, 665687, 709000 2.8.1.9 metabolism molybdenum-cofactor sulfurase is a key regulator of abscisic acid biosynthesis 726237 2.8.1.9 physiological function endogenous levels of anthocyanins are significantly lower in the ABA3 mutant than in the wild type or an xanthoxin dehydrogenase ABA2 mutant under oxidative stress. Mutants defective in the aldehyde oxidase and xanthine dehydrogenase holoenzymes accumulate significantly higher levels of anthocyanins when compared with the ABA3 mutant under the same conditions 762449 2.8.1.9 physiological function enzyme overexpression in transgenic tobacco can enhance drought tolerance. Enzyme overexpressing tobacco seedlings show lower transpirational water loss than that of nontransgenic seedlings in the same period under normal conditions. Transgenic plants show less wilting, maintain higher water content and better cellular membrane integrity, accumulate higher quantities of abscisic acid and proline, and exhibit higher activities of antioxidant enzymes, i.e., superoxide dismutase, catalase, peroxidase and ascorbate peroxidase, as compared with control plants 726237 2.8.1.9 physiological function overexpression in Sesamum indicum. Under severe drought conditions, transgenic plants show less reduction in height compared to azygous non-transgenic plants. Increase in total extractable soluble proteins, elevation in proline accumulation, and a reduction in MDA levels are recorded in transgenic lines. Under non-stressed conditions, ascorbate peroxidase, catalase, peroxidase and superoxide dismutase activity levels increase by 25%, 23%, 210% and 75%, respectively, compared to azygous non-transgenic plants 760745 2.8.1.9 physiological function overexpression of Arabidopsis molybdenum cofactor sulfurase gene LOS5 in maize markedly enhances the expression and activity of aldehyde oxidase, leading to absisic acid accumulation and increased drought tolerance by decreasing stomatal aperture to reduce water loss. LOS5 overexpression enhances abiotic stress-related genes 726315 2.8.1.9 physiological function the enzyme enhances the tolerance to high salt, cold, osmotic stresses, and abscisic acid induction 739285 2.8.1.9 physiological function the enzyme is involved in aldehyde oxidase activity in Arabidopsis, which indirectly regulates absisic acid biosynthesis and increases stress tolerance. Overexpression of the enzyme prevents water loss and modulates stomatal closure, enhances expression of stress-upregulated genes and promotes absisic acid accumulation to drought stress. Enzyme overexpression also enhances biomass accumulation and produces higher yield in the field 726131