2.4.1.364 metabolism key enzyme for the synthesis of ginsenosides 751849 2.4.1.364 physiological function overexpression of Pq3-O-UGT1 leads to a higher level of protopanaxadiol-group ginsenosides (especially for Rh2 and Rd) in transgenic hairy roots, whereas RNA interference against Pq3-O-UGT1 results in lower content of ginsenoside Rh2. Both overexpression and RNAi upregulate the key upstream genes Pq-D12H and Pq-CYP6H, and there is no effect on the upstream gene of Pq-DS 759949