1.2.7.8 malfunction Methanococcus maripaludis has two IOR homologs. A deletion mutant for one of these homologs contains 76, 74, and 42% lower activity for phenylpyruvate, p-hydroxyphenylpyruvate, and indolepyruvate oxidation, respectively, than the wild type. Growth of this mutant in minimal medium is inhibited by the aryl acids, but the aromatic amino aciuds partially restore growth 727742