1.14.15.29	metabolism	CYP125 performs an obligate first step in cholesterol degradation. CYP125 is involved in steroid C26-carboxylic acid formation, catalysing the oxidation of C26 either to the corresponding carboxylic acid or to an intermediate state	718126	
1.14.15.29	metabolism	CYP125A1 is a key enzyme in cholesterol metabolism and plays a crucial role in circumventing the deleterious effect of cholest-4-en-3-one	-, 718129	
1.14.15.29	physiological function	cyp125 is essential for Rhodococcus jostii strain RHA1 to grow on 3-hydroxysterols such as cholesterol, but not on 3-oxo sterol derivatives	718126	
1.14.15.29	physiological function	Cyp125 is essential for the growth of Mycobacterium bovis strain bacillus Calmette-Guerin on cholesterol	-, 717783	
1.14.15.29	physiological function	Cyp125 is not essential for the growth of Mycobacterium tuberculosis on cholesterol	-, 717783	
1.14.15.29	physiological function	CYP125A1 is required to incorporate the cholesterol side chain carbon atoms into cellular lipids. CYP125A1 is essential for growth of CDC1551 in media containing cholesterol or cholest-4-en-3-one	-, 718129