4.2.1.46 malfunction inactivation of rmbB abolishes the production of doxorubicin while complementation of the same gene in an rmbB knockout mutant restores the doxorubicin production 701859 4.2.1.46 metabolism the enzyme is involved in biosynthesis of dTDP-L-rhamnose, which is a sugar donor to the synthesis of the cell wall linker, D-N-acetylglucosamine-L-rhamnose -, 746731 4.2.1.46 metabolism the enzyme is involved in the biosynthesis of the dTDP-3-amino-3,6-dideoxy-D-galactose and dTDP-3-amino-3,6-dideoxy-D-glucose 747917 4.2.1.46 metabolism the enzyme is involved in the dTDP-rhamnose biosynthetic pathway 747027 4.2.1.46 physiological function rmbB provides dTDP-4-dehydro-6-deoxy-D-glucose as a nucleotide sugar precursor for the biosynthesis of doxorubicin 701859