3.6.1.43 malfunction in enzyme-deficient cells showing endoplasmic reticulum stress, membrane and growth defect, the N-glycosylation of the vacuolar carboxypeptidase is severely affected, and expression of the endoplasmic reticulum chaperone Kar2p is elevated, which results in unfolded protein response activation as an adaptive response -, 756082 3.6.1.43 metabolism olicholpyrophosphatase participates in glycoprotein biosynthesis 711954 3.6.1.43 metabolism the enzyme is essential for phospholipid homeostasis -, 756082 3.6.1.43 physiological function the enzyme regulates membrane biogenesis by coordinating lipid homeostasis with protein quality control -, 756082