2.1.1.158	metabolism	methylation of xanthosine by 7-methylxanthosine synthase is the most plausible rate-limiting step of caffeine biosynthesis, the supply of non-methylated purine precursors or availability of S-adenosyl-L-methionine are not the principal controlling factors of caffeine biosynthesis	700656	
2.1.1.158	metabolism	the enzyme catalyzes the first step in caffeine biosynthesis, pathway overview	721124