1.17.9.1 malfunction using a gene-knockout it is shown that PCMH-encoding gene pchF is necessary for the catabolism of 2,4-xylenol 726788 1.17.9.1 metabolism PCMH is a key enzyme responsible for the catabolism of p-cresol via the protocatechuate ortho pathway, pathway overview -, 715044 1.17.9.1 metabolism the enzyme is necessary for 2,4-xylenol catabolism -, 744141 1.17.9.1 additional information transcriptional regulation of the pchACXF operon by PchR, a putative sigma54-dependent regulator, overview. Phenol does not activate the regulator of PC24, and both regulators respond similarly to p-cresol -, 715044 1.17.9.1 additional information transcriptional regulation of the pchACXF operon by PchR, a putative sigma54-dependent regulator, overview. Phenol is a more efficient effector for PchR of PC18 than p-cresol -, 715044