3.4.23.36	malfunction	a cell wall permeability defect is likely responsible for the hypersensitivity of lspA mutant to malachite green	
3.4.23.36	malfunction	mutations generated in the lspA gene result in the ablation of Streptococcus gordonii-cAM373 activity in culture supernatants	
3.4.23.36	malfunction	mutations in lspA gene reduce competitiveness by 2-3fold in the animal model and in broth culture, the lspA mutant has a general defect in lipoprotein cleavage	
3.4.23.36	malfunction	enzyme deficiency leads to a partial loss of elongated spermatids and reduced motility of mature spermatozoa, but preserved fertility	
3.4.23.36	malfunction	enzyme downregulation suppresses tumor cell colony formation, migration, and invasion in vitro	
3.4.23.36	physiological function	lipoprotein processing by lipoprotein signal peptidase II is essential for resistance of Mycobacterium tuberculosis to malachite green	
3.4.23.36	physiological function	overexpression of signal peptides II specifically confers TA resistance to Escherichia coli	
3.4.23.36	physiological function	the enzyme promotes male germ cell development by cleavingxa0phospholamban	
3.4.23.36	physiological function	the enzyme promotes tumor progression via facilitating FKBP8 degradation