3.3.2.1	metabolism	the biosynthesis of salicylic acid in plants occurs through phenylpropanoid and isochorismate pathways	
3.3.2.1	additional information	isochorismatase domains of AngB and VabB from Vibrio anguillarum, which are required to synthesize the critical virulence factor siderophore, are highly similar to known isochorismatases in fold and active site. Active site structure analysis, overview	
3.3.2.1	physiological function	isochorismatase hydrolase may be acting as a plant-defense suppressor produced by the highly aggressive isolate to overcome host resistance	
3.3.2.1	physiological function	isochorismatase (ISC) converts isochorismate to (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate, which is a critical step for the siderophore synthesis. Two different siderophores, anguibactin and vanchrobactin, are described in Vibrio anguillarum, both siderophores belong to the catecholate group, sharing a 2,3-dihydroxybenzoic acid (DHBA) moiety