3.2.1.145	evolution	the enzyme belongs to the glycoside hydrolase family 43, GH43	732396	
3.2.1.145	evolution	the enzyme belongs to the glycoside hydrolase family 43, GH43, phylogenetic analysis and tree	-, 731581	
3.2.1.145	evolution	the enzyme belongs to the glycoside hydrolase family 43, GH43, phylogenetic relationships of BLLJ_1840	-, 731184	
3.2.1.145	evolution	the enzyme belongs to the glycosyl hydrolase family 30, GH30, subfamily 22. GH43_24 exo-beta-1,3-galactanase (Bl1,3Gal, EC 3.2.1.145) forms a gene cluster with GH30_5 and GH43_22 enzyme candidates, which are conserved in all Bifidobacterium longum strains	752571	
3.2.1.145	evolution	the enzyme belongs to the glycosyl hydrolase family 43, GH43, subfamily 24. GH43_24 exo-beta-1,3-galactanase (Bl1,3Gal) forms a gene cluster with GH30_5 exo-beta-1,6-galactobiohydrolase (Bl1,6Gal) and GH43_22 alpha-L-arabinofuranosidase (BlArafA) enzyme candidates, which are conserved in all Bifidobacterium longum strains	752571	
3.2.1.145	evolution	the enzyme belongs to the glycosyl hydrolase family 43, GH43. Structure comparisons reveal that structural and sequence homology between BbGal43A, Clostridium thermocellum Ct1,3Gal43A (PDB ID 3vsf), and Bacteroides thetaiotaomicron BT2959 (PDB ID 3nqh) indicate that all three enzymes might be different types of exo-beta-1,3-galactanase	-, 752397	
3.2.1.145	metabolism	GH30_5 exo-beta-1,6-galactobiohydrolase (Bl1,6Gal, EC 3.2.1.145) and GH43_22 alpha-L-arabinofuranosidase (BlArafA, EC 3.2.1.55) are degradative enzymes for type II arabinogalactan (AG) side chains in cooperation with GH43_24 exo-beta-1,3-galactanase (Bl1,3Gal, EC 3.2.1.145)	752571	
3.2.1.145	metabolism	GH30_5 exo-beta-1,6-galactobiohydrolase (Bl1,6Gal, EC 3.2.1.145) and GH43_22 alpha-L-arabinofuranosidase (BlArafA, EC 3.2.1.55), which are degradative enzymes for type II arabinogalactan (AG) side chains in cooperation with GH43_24 exo-beta-1,3-galactanase (Bl1,3Gal, EC 3.2.1.145)	752571	
3.2.1.145	metabolism	the enzyme shows a synergistic effect with related enzymes on degradation of type II arabinogalactan	-, 731202	
3.2.1.145	additional information	domain structures of BLLJ_1840 comprising the GH43 catalytic domain, bacterial Ig-like domain, CBM32, and the LPXTG cell wall anchor domain (Anchor), as well as the signal peptide	-, 731184	
3.2.1.145	additional information	two modes of substrate binding are observed at the beta site of the CtCBM13 domain, and one galactobiose molecule is found in an L shaped pocket of the CtGH43 domain, which appears large enough to accommodate two more galactose units. Glu112 serves as the general base for substrate hydrolysis. Putative mechanism of substrate delivery via the CBM13 domain, overview	732396	
3.2.1.145	physiological function	type II arabinogalactan (AG) degradative enzymes, including Bl1,3Gal, Bl1,6Gal, and BlArafA. GH30_5 exo-beta-1,6-galactobiohydrolase (Bl1,6Gal, EC 3.2.1.145) and GH43_22 alpha-L-arabinofuranosidase (BlArafA, EC 3.2.1.55) are important for the acquisition of type II AG in Bifidobacterium longum	752571