1.14.20.4	malfunction	an insertion in the PgLDOX gene (leucoanthocyanidin dioxygenase/anthocyanidin synthase) is responsible for the white anthocyanin-less phenotype. None of the analyzed white pomegranate tissues are able to synthesize mRNA corresponding to the PgLDOX gene	743595	
1.14.20.4	malfunction	lack of enzyme encoding gene BjANS expression blocks biosynthesis of proanthocyanidins in the yellow seed coat, and therefore seeds appear yellow because of transparent testa	725953	
1.14.20.4	malfunction	two inactive alleles are reported: a mutant anthocyanidin synthase allele containing a 4-bp insertion at the end of exon1 is identified from yellow bulbs of the F2 population in which the DFR-A (dihydroflavonol 4-reductase) genotype is homozygous for an active allele. The 4-bp insertion causes a frame-shift mutation and results in creation of a premature stop codon at the start of exon2. This mutant anthocyanidin synthase allele is designated ANSPS allele. RT-PCR results show that transcripts of the ANSPS allele are almost undetectable in yellow F2 bulbs, implying the involvement of nonsense-mediated mRNA decay. Another inactive anthocyanidin synthase allele is identified from the light-red F1 populations showing complementation between DFR-A (dihydroflavonol 4-reductase) and anthocyanidin synthase genes. A critical amino acid change of the strictly conserved serine residue into leucine is found in this mutant allele designated ANSS188L	742427	
1.14.20.4	metabolism	anthocyanidin synthase is one of the key enzymes in the biosynthesis of both anthocyanins and proanthocyanidins in grapevine	-, 713486	
1.14.20.4	metabolism	anthocyanidin synthase is the key enzyme in anthocyanin biosynthesis	743789	
1.14.20.4	metabolism	anthocyanidin synthase, a 2-oxoglutarate iron-dependent oxygenase, converts leucoanthocyanidins into 3-hydroxyanthocyanidin in late flavonoid biosynthesis	725953	
1.14.20.4	metabolism	key enzyme in biosynthesis of anthocyanins	742599	
1.14.20.4	metabolism	part of flavonoid biosynthetic pathway	701213	
1.14.20.4	metabolism	Reaumuria trigyna leucoanthocyanidin dioxygenase is one of three dioxygenases in the flavonoid pathway that catalyzes the formation of anthocyanidins from leucoanthocyanidins. It is involved in enhancing plant response to NaCl stress	743507	
1.14.20.4	metabolism	the enzyme catalyzes the conversion of colorless leucoanthocyanins into colored anthocyanins	741645	
1.14.20.4	metabolism	the enzyme catalyzes the penultimate step in anthocyanin biosynthesis, from leucoanthocyanidins to anthocyanidins, the first colored compound in the anthocyanin pathway	742619	
1.14.20.4	metabolism	the enzyme is involved in the anthocyanin biosynthesis pathway	743595	
1.14.20.4	metabolism	the enzyme plays a pivotal role in anthocyanin biosynthesis. It is responsible for anthocyanin accumulation during petal coloration in different crabapple cultivars	741548	
1.14.20.4	physiological function	flavonol synthase activity, correspondending to EC 1.14.11.23, in case of mutants lacking the active flavonol synthase 1	697947	
1.14.20.4	physiological function	flavonol synthase-like side activity	700864	
1.14.20.4	physiological function	overexpression of ANS in tobacco results in increased content of both anthocyanidins and proanthocyanidins in flower petals. Overexpression in an Arabidopsis ldox mutant complements its proanthocyanidin deficient phenotype in seeds	744602	
1.14.20.4	physiological function	the enzyme is involved in the biosynthesis of proanthocyanidins and in seed coat color formation	725953	
1.14.20.4	physiological function	the expression of ANS genes ANS1 and ANS2 in three cultivars with dark red (Royalty) and white (Flame) petals, as well as another (Radiant) whose petals have an intermediate pink color, correlates with the variation of anthocyanin accumulation during different petal developmental stages. Transgenic tobacco plants constitutively overexpressing ANS1 shows elevated anthocyanin accumulation and a deeper red coloration in their petals than those from untransformed control lines	741548	
1.14.20.4	physiological function	the expression of ANS genes ANS1 and ANS2 in three cultivars with dark red and white petals, as well as another whose petals have an intermediate pink color, correlates with the variation of anthocyanin accumulation during different petal developmental stages	741548	
1.14.20.4	physiological function	transgenic expression in Fragaria ananassa. The expression of genes encoding enzymes of two early steps on the phenylpropanoids pathway, phenylalanine ammonia-lyase and cinnamic acid 4-hydroxylase, is significantly up-regulated in transgenic lines. The expression of two cinnamyl alcohol dehydrogenase genes, also involved in the phenylpropanoid pathway, is largely reduced in ANS lines	745148