3.5.4.6	down	during pregnancy the activity of AMP-deaminase in developing human placenta gradually decreases, being in homogenates of mature, term placenta (about 40 weeks of gestation) one fourth to one third of that in homogenates of immature (about 25 weeks of gestation) organ	713244	
3.5.4.6	up	AMP deaminase in the liver is elevated by 4.2fold in models of hepatotoxic injury as compared with controls. In acute hyperammonemia, activity of AMP deaminase increases by 59% in the neocortex. In the hippocampus of hyperammonemic rats, AMP deaminase activity is increased by 48%. Subacute hepatitis leads to 228% increase in AMP deaminase activity	711639	
3.5.4.6	up	induction with 0.75 mM isopropyl beta-D-l-thiogalactopyranoside results in an enzyme activity of 1773.9 U/ml	-, 755821