2.3.1.297 down ceramide synthase 2 activity is significantly reduced in the testes of acyl-coenzyme A-binding protein-deficient mice 754160 2.3.1.297 up ionizing radiation (IR) induces de novo synthesis of ceramide by specifically activating CerS isoforms 2, 5, and 6 753223 2.3.1.297 up the mRNA level of the enzyme increases 1.23fold in the presence of 0.03 mM Asterias amurensis-derived sphingoid bases 757470 2.3.1.297 up UV-C irradiation increases the enzyme expression by 1.27fold 754096