1.6.3.5	down	gonadotropin-releasing hormone antagonist, cetrorelix, represses renalase expression in mice ovaries and testes	728281	
1.6.3.5	up	knockout of leptin, an effector and modulator of steroid hormones and reproduction, causes a dramatic increase of renalase expression in mice testes	728281	
1.6.3.5	up	renalase expression is significantly increased in cancers of the pancreas, bladder and breast and in melanoma	742961	
1.6.3.5	up	the secretion of renalase in both plasma and urine is increased in patients with chronic kidney disease	742454