1.1.1.53 additional information expressed during embryonic development 725963 1.1.1.53 up transcripts are up-regulated upon cortisol treatment. A cortisol-independent, short-term physical stressor leads to the up-regulation of isoforms 11beta-HSD2 and 20beta-HSD2 expression along with several hypothalamus-pituitary-interrenal axis genes 726321