2.3.1.297	down	ceramide synthase 2 activity is significantly reduced in the testes of acyl-coenzyme A-binding protein-deficient mice	
2.3.1.297	up	ionizing radiation (IR) induces de novo synthesis of ceramide by specifically activating CerS isoforms 2, 5, and 6	
2.3.1.297	up	UV-C irradiation increases the enzyme expression by 1.27fold	
2.3.1.297	up	the mRNA level of the enzyme increases 1.23fold in the presence of 0.03 mM Asterias amurensis-derived sphingoid bases