2.1.1.5	down	corticosteroids down-regulate in kidney expression and activity	720080	
2.1.1.5	down	decreased expression after exogenous addition of all-trans-retinoic acid	704793	
2.1.1.5	additional information	during fetal development, a total of ten splice variants of BHMT are expressed at varying levels across a wide range of porcine tissues. Two variants contain an identical ORF that encodes a C-terminal truncated form of BHMT	733936	
2.1.1.5	up	corticosteroids stimulate activity in the liver and also up-regulate the gene expression	720080	
2.1.1.5	up	significant upregulation of betaine homocysteine methyltransferase-1 in livers of rats fed a betaine supplemented ethanol diet	702044	
2.1.1.5	up	the activity of hepatic BHMT significantly increases with increase in both dietary casein level and dietary methionine level, hepatic level of mRNA for BHMT is parallel to the enzyme activity	705295