2.5.1.59 758655 Inhibiting fungal echinocandin resistance by small-molecule disruption of geranylgeranyltransferase type i activity Antimicrob. Agents Chemother. 64 e02046-19 2020 [Candida] glabrata http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31791942&form=6&db=m 2.5.1.59 758655 Inhibiting fungal echinocandin resistance by small-molecule disruption of geranylgeranyltransferase type i activity Antimicrob. Agents Chemother. 64 e02046-19 2020 Candida parapsilosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31791942&form=6&db=m 2.5.1.59 758655 Inhibiting fungal echinocandin resistance by small-molecule disruption of geranylgeranyltransferase type i activity Antimicrob. Agents Chemother. 64 e02046-19 2020 Candida tropicalis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31791942&form=6&db=m 2.5.1.59 758655 Inhibiting fungal echinocandin resistance by small-molecule disruption of geranylgeranyltransferase type i activity Antimicrob. Agents Chemother. 64 e02046-19 2020 Candida albicans http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31791942&form=6&db=m 2.5.1.59 758828 Protein farnesyltransferase catalyzes unanticipated farnesylation and geranylgeranylation of shortened target sequences Biochemistry 59 1149-1162 2020 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32125828&form=6&db=m 2.5.1.59 759142 Pyrazole-based potent inhibitors of GGT1 Synthesis, biological evaluation, and molecular docking studies Eur. J. Med. Chem. 124 666-676 2016 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27620969&form=6&db=m 2.5.1.59 636546 Active site determination of yeast geranylgeranyl protein transferase type I expressed in Escherichia coli Eur. J. Biochem. 265 105-111 1999 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10491163&form=6&db=m 2.5.1.59 660285 Characterisation of CaaX-prenyltransferases in Catharanthus roseus: relationships with the expression of genes involved in the early stages of monoterpenoid biosynthetic pathway Plant Sci. 168 1097-1107 2005 Catharanthus roseus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=100125035&form=6&db=m 2.5.1.59 636542 Characterization of Ha-Ras, N-Ras, Ki-Ras4A, and Ki-Ras4B as in vitro substrates for farnesyl protein transferase and geranylgeranyl protein transferase type I J. Biol. Chem. 272 10232-10239 1997 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9092572&form=6&db=m 2.5.1.59 636549 Characterization of the geranylgeranyl transferase type I from Schizosaccharomyces pombe Mol. Microbiol. 29 1357-1367 1998 Schizosaccharomyces pombe http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9781874&form=6&db=m