2.1.2.3	756109	 Analysis of substrate binding in individual active sites of bifunctional human ATIC	Biochim. Biophys. Acta	 1866	 254-263 	2018	Homo sapiens	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29042184&form=6&db=m	
2.1.2.3	756701	 Characterization of AICAR transformylase/IMP cyclohydrolase (ATIC) from Staphylococcus lugdunensis	FEBS J.	 284	 4233-4261 	2017	Staphylococcus lugdunensis	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29063699&form=6&db=m	
2.1.2.3	756196	 Colocalization and sequential enzyme activity in aqueous biphasic systems	 experiments and modeling	Biophys. J.	 109	 2182-2194 	2015	Homo sapiens	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26588576&form=6&db=m	
2.1.2.3	756643	 Design, synthesis and biological evaluation of 6-substituted pyrrolo[2,3-d]pyrimidines as dual inhibitors of TS and AICARFTase and as potential antitumor agents	Eur. J. Med. Chem.	 115	 245-256 	2016	Homo sapiens	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27017552&form=6&db=m	
2.1.2.3	757394	 Discovery of N-(6-fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a potent and selective nonclassical antifolate aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT) inhibitor	J. Med. Chem.	 60	 9599-9616 	2017	Homo sapiens	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29072452&form=6&db=m	
2.1.2.3	757213	 High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans	J. Biol. Chem.	 293	 4845-4859 	2018	Caenorhabditis elegans	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29414769&form=6&db=m	
2.1.2.3	756648	 Novel 6-substituted benzoyl and non-benzoyl straight chain pyrrolo[2,3-d]pyrimidines as potential antitumor agents with multitargeted inhibition of TS, GARFTase and AICARFTase	Eur. J. Med. Chem.	 139	 531-541 	2017	Homo sapiens	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28830032&form=6&db=m	
2.1.2.3	757662	 The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network	Mol. Cell. Proteomics	 14	 1079-1092 	2015	Rattus norvegicus	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25687571&form=6&db=m	
2.1.2.3	757625	 Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia coli	Microbiology	 164	 982-991 	2018	Escherichia coli	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29799386&form=6&db=m	
2.1.2.3	757625	 Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia coli	Microbiology	 164	 982-991 	2018	Escherichia coli K12	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29799386&form=6&db=m