3.4.22.58 647721 Molecular cloning and pro-apoptotic activity of ICErelII and ICErelIII, members of the ICE/CED-3 family of cysteine proteases J. Biol. Chem. 270 15870-15876 1995 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7797592&form=6&db=m 3.4.22.58 647720 Identification of a cysteine protease closely related to interleukin-1 beta-converting enzyme Eur. J. Biochem. 236 207-213 1996 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8617266&form=6&db=m 3.4.22.58 647706 Identification and characterization of Ich-3, a member of the interleukin-1beta converting enzyme (ICE)/Ced-3 family and an upstream regulator of ICE J. Biol. Chem. 271 20580-20587 1996 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8702803&form=6&db=m 3.4.22.58 647429 A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis J. Biol. Chem. 272 17907-17911 1997 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9218414&form=6&db=m 3.4.22.58 647724 Enzymic activity of two caspases related to interleukin-1beta-converting enzyme Eur. J. Biochem. 253 76-83 1998 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9578463&form=6&db=m 3.4.22.58 647423 Inhibition of human caspases by peptide-based and macromolecular inhibitors J. Biol. Chem. 273 32608-32613 1998 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9829999&form=6&db=m 3.4.22.58 647424 Purification and catalytic properties of human caspase family members Cell Death Differ. 6 362-369 1999 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10381624&form=6&db=m 3.4.22.58 647428 Proteases from cell suicide: functions and regulation of caspases Microbiol. Mol. Biol. Rev. 64 821-846 2000 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11104820&form=6&db=m 3.4.22.58 665234 BAX and caspase-5 frameshift mutations and spontaneous apoptosis in colorectal cancer with microsatellite instability Int. J. Colorectal Dis. 19 538-544 2004 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15088110&form=6&db=m 3.4.22.58 666306 Repeated sequences in CASPASE-5 and FANCD2 but not NF1 are targets for mutation in microsatellite-unstable acute leukemia/myelodysplastic syndrome Mol. Cancer Res. 3 251-260 2005 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15886296&form=6&db=m