4.2.3.5 746806 Comparative analysis of mono- and bifunctional chorismate synthases in Escherichia coli cells capable and incapable of phenylalanine production Appl. Biochem. Microbiol. 53 867-873 2017 Saccharomyces cerevisiae - 4.2.3.5 746806 Comparative analysis of mono- and bifunctional chorismate synthases in Escherichia coli cells capable and incapable of phenylalanine production Appl. Biochem. Microbiol. 53 867-873 2017 Escherichia coli - 4.2.3.5 746681 Effect of temperature and cut size on the volatile organic compound profile, and expression of chorismate synthase in fresh-cut melon Acta Hortic. 1194 1175-1180 2018 Cucumis melo - 4.2.3.5 747928 Structural analysis and molecular docking of potential ligands with chorismate synthase of Listeria monocytogenes a novel antibacterial drug target Indian J. Biochem. Biophys. 52 45-59 2015 Listeria monocytogenes http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26040111&form=6&db=m 4.2.3.5 747928 Structural analysis and molecular docking of potential ligands with chorismate synthase of Listeria monocytogenes a novel antibacterial drug target Indian J. Biochem. Biophys. 52 45-59 2015 Listeria monocytogenes F2365 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26040111&form=6&db=m 4.2.3.5 650514 A secondary beta deuterium kinetic isotope effect in the chorismate synthase reaction Bioorg. Chem. 28 191-204 2000 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11034781&form=6&db=m 4.2.3.5 650514 A secondary beta deuterium kinetic isotope effect in the chorismate synthase reaction Bioorg. Chem. 28 191-204 2000 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11034781&form=6&db=m 4.2.3.5 137647 A simple anaerobic assay for chorismate synthase Biochem. Soc. Trans. 15 144-145 1978 Bacillus subtilis - 4.2.3.5 137647 A simple anaerobic assay for chorismate synthase Biochem. Soc. Trans. 15 144-145 1978 Escherichia coli - 4.2.3.5 137647 A simple anaerobic assay for chorismate synthase Biochem. Soc. Trans. 15 144-145 1978 Neurospora crassa - 4.2.3.5 679351 A structural model for chorismate synthase from Mycobacterium tuberculosis in complex with coenzyme and substrate Comput. Biol. Med. 37 149-158 2007 Mycobacterium tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16584721&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Euglena gracilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Solanum lycopersicum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Staphylococcus aureus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Capnoides sempervirens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Bacillus subtilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 653564 A unique reaction in a common pathway. Mechanism and function of chorismate synthase in the shikimate pathway Planta 207 325-334 1999 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9951731&form=6&db=m 4.2.3.5 137661 Chorismate synthase from Staphylococcus aureus Microbiology 142 2943-2950 1996 Staphylococcus aureus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8885411&form=6&db=m 4.2.3.5 652121 Chorismate synthase from the hyperthermophile Thermotoga maritima combines thermostability and increased rigidity with catalytic and spectral properties similar to mesophilic counterparts J. Biol. Chem. 276 18052-18059 2001 Thermotoga maritima http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11279147&form=6&db=m 4.2.3.5 137651 Chorismate synthase of Neurospora crassa: A flavoprotein Arch. Biochem. Biophys. 165 505-518 1974 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4155270&form=6&db=m 4.2.3.5 137646 Chorismate synthase: A bifunctional enzyme in Neurospora crassa Methods Enzymol. 142 362-366 1987 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2955201&form=6&db=m 4.2.3.5 679365 Chorismate synthase: an attractive target for drug development against orphan diseases Curr. Drug Targets 8 437-444 2007 Streptococcus pneumoniae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17348836&form=6&db=m 4.2.3.5 679365 Chorismate synthase: an attractive target for drug development against orphan diseases Curr. Drug Targets 8 437-444 2007 Salmonella enterica http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17348836&form=6&db=m 4.2.3.5 679365 Chorismate synthase: an attractive target for drug development against orphan diseases Curr. Drug Targets 8 437-444 2007 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17348836&form=6&db=m 4.2.3.5 679365 Chorismate synthase: an attractive target for drug development against orphan diseases Curr. Drug Targets 8 437-444 2007 Yersinia enterocolitica http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17348836&form=6&db=m 4.2.3.5 679365 Chorismate synthase: an attractive target for drug development against orphan diseases Curr. Drug Targets 8 437-444 2007 Brucella suis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17348836&form=6&db=m 4.2.3.5 137658 Cloning and characterization of a heterologously expressed bifunctional chorismate synthase/flavin reductase from Neurospora crassa J. Biol. Chem. 270 20447-20452 1995 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7657620&form=6&db=m 4.2.3.5 137649 Cloning and overexpression of the Escherichia coli aroC gene encoding the enzyme chorismate synthase Biochem. Soc. Trans. 14 262-263 1986 Escherichia coli - 4.2.3.5 729586 Comparison of DFT and ab initio QM/MM methods for modelling reaction in chorismate synthase Chem. Phys. Lett. 608 380-385 2014 Streptococcus pneumoniae - 4.2.3.5 682003 Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway Mol. Microbiol. 65 1249-1257 2007 Bacillus subtilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17662045&form=6&db=m 4.2.3.5 682003 Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway Mol. Microbiol. 65 1249-1257 2007 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17662045&form=6&db=m 4.2.3.5 682003 Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway Mol. Microbiol. 65 1249-1257 2007 Solanum lycopersicum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17662045&form=6&db=m 4.2.3.5 682003 Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway Mol. Microbiol. 65 1249-1257 2007 Plasmodium falciparum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17662045&form=6&db=m 4.2.3.5 682003 Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway Mol. Microbiol. 65 1249-1257 2007 Tetrahymena thermophila http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17662045&form=6&db=m 4.2.3.5 682003 Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway Mol. Microbiol. 65 1249-1257 2007 Toxoplasma gondii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17662045&form=6&db=m 4.2.3.5 682003 Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway Mol. Microbiol. 65 1249-1257 2007 Vitis vinifera http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17662045&form=6&db=m 4.2.3.5 653841 Crystal structure of chorismate synthase from Aquifex aeolicus reveals a novel beta alpha beta sandwich topology Proteins Struct. Funct. Bioinform. 54 166-169 2003 Aquifex aeolicus - 4.2.3.5 652935 Crystal structure of chorismate synthase: a novel FMN-binding protein fold and functional insights J. Mol. Biol. 336 903-915 2004 Helicobacter pylori http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15095868&form=6&db=m 4.2.3.5 652559 Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae J. Biol. Chem. 279 619-625 2004 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14573601&form=6&db=m 4.2.3.5 649228 Crystallization and preliminary X-ray crystallographic studies of chorismate synthase from Helicobacter pylori Acta Crystallogr. Sect. D 59 569-571 2003 Helicobacter pylori http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12595729&form=6&db=m 4.2.3.5 137636 Dehydroquinate synthase in Bacillus subtilis. An enzyme associated with chorismate synthase and flavin reductase J. Biol. Chem. 253 4999-5004 1978 Bacillus subtilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=97286&form=6&db=m 4.2.3.5 137648 Detection and subcellular localization of a higher plant chorismate synthase FEBS Lett. 205 328-332 1986 Pisum sativum - 4.2.3.5 137660 Differential expression of tomato (Lycopersicon esculentum L.) genes encoding shikimate pathway isoenzymes. II. Chorismate synthase Plant Mol. Biol. 23 707-716 1993 Solanum lycopersicum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8251624&form=6&db=m 4.2.3.5 137664 Enzymatic properties of chorismate synthase isozymes of tomato (Lycopersicon esculentum Mill.) Planta 200 64-70 1996 Solanum lycopersicum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8987618&form=6&db=m 4.2.3.5 137657 Escherichia coli chorismate synthase catalyzes the conversion of (6S)-6-fluoro-5-enolpyruvylshikimate-3-phosphate to 6-fluorochorismate. Implications for the enzyme mechanism and the antimicrobial action of (6S)-6-fluoroshikimate J. Biol. Chem. 270 22811-22815 1995 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7559411&form=6&db=m 4.2.3.5 137656 Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding Biochem. J. 335 319-327 1998 Escherichia coli - 4.2.3.5 730336 Functional analysis of the aroC gene encoding chorismate synthase from Xanthomonas oryzae pathovar oryzae Microbiol. Res. 167 326-331 2012 Xanthomonas oryzae pv. oryzae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22169355&form=6&db=m 4.2.3.5 730336 Functional analysis of the aroC gene encoding chorismate synthase from Xanthomonas oryzae pathovar oryzae Microbiol. Res. 167 326-331 2012 Xanthomonas oryzae pv. oryzae KACC10859 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22169355&form=6&db=m 4.2.3.5 705812 Functional contribution of chorismate synthase, anthranilate synthase, and chorismate mutase to penetration resistance in barley-powdery mildew interactions Mol. Plant Microbe Interact. 22 311-320 2009 Hordeum vulgare http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19245325&form=6&db=m 4.2.3.5 681499 Homology modeling and molecular dynamics study of chorismate synthase from Shigella flexneri J. Mol. Graph. Model. 25 434-441 2006 Shigella flexneri http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16616535&form=6&db=m 4.2.3.5 652570 Mechanism of chorismate synthase. Role of the two invariant histidine residues in the active site J. Biol. Chem. 279 9451-9461 2004 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14668332&form=6&db=m 4.2.3.5 678265 Mutagenic analysis of an invariant aspartate residue in chorismate synthase supports its role as an active site base Biochemistry 46 3768-3774 2007 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17326665&form=6&db=m 4.2.3.5 137662 Only the mature form of the plastidic chorismate synthase is enzymatically active Plant Physiol. 108 1127-1132 1995 Capnoides sempervirens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12228531&form=6&db=m 4.2.3.5 137652 Properties of chorismate synthase in Neurospora crassa J. Biol. Chem. 248 4602-4609 1973 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4146266&form=6&db=m 4.2.3.5 137663 Purification and characterization of chorismate synthase from Euglena gracilis Plant Physiol. 97 1271-1279 1991 Euglena gracilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16668543&form=6&db=m 4.2.3.5 137650 Purification and properties of chorismate synthase from Bacillus subtilis J. Biol. Chem. 253 4993-4998 1978 Bacillus subtilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=97285&form=6&db=m 4.2.3.5 137666 Purification of chorismate synthase from a cell culture of the higher plant Corydalis sempervirens Pers Arch. Biochem. Biophys. 282 437-442 1990 Capnoides sempervirens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2146922&form=6&db=m 4.2.3.5 692285 Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity FEBS J. 275 1464-1473 2008 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18279385&form=6&db=m 4.2.3.5 137659 Saccharomyces cerevisiae chorismate synthase has a flavin reductase activity Mol. Microbiol. 22 859-866 1996 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8971708&form=6&db=m 4.2.3.5 701862 Silencing of Vlaro2 for chorismate synthase revealed that the phytopathogen Verticillium longisporum induces the cross-pathway control in the xylem Appl. Microbiol. Biotechnol. 85 1961-1976 2010 Verticillium longisporum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19826808&form=6&db=m 4.2.3.5 652195 Spectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH J. Biol. Chem. 276 42658-42666 2001 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11526120&form=6&db=m 4.2.3.5 137653 Stereochemistry of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase reaction and the chorismate synthetase reaction J. Biol. Chem. 247 736-744 1972 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4550759&form=6&db=m 4.2.3.5 715196 Structural analysis of chorismate synthase from Plasmodium falciparum: A novel target for antimalaria drug discovery Int. J. Biol. Macromol. 49 767-777 2011 Plasmodium falciparum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21801743&form=6&db=m 4.2.3.5 666176 Structure of chorismate synthase from Mycobacterium tuberculosis J. Struct. Biol. 154 130-143 2006 Mycobacterium tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16459102&form=6&db=m 4.2.3.5 652056 Studies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reaction J. Biol. Chem. 275 35825-35830 2000 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10956653&form=6&db=m 4.2.3.5 653268 Subcellular localization and characterization of chorismate synthase in the apicomplexan Plasmodium falciparum Mol. Microbiol. 40 65-75 2001 Plasmodium falciparum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11298276&form=6&db=m 4.2.3.5 137655 The enzymic synthesis of chorismic and prephenic acids from 3-enolpyruvylshikimic acid 5-phosphate J. Biol. Chem. 242 82-90 1967 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4289188&form=6&db=m 4.2.3.5 691478 The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase BMC Biochem. 9 13 2008 Mycobacterium tuberculosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18445278&form=6&db=m 4.2.3.5 137645 The overexpression, purification and complete amino acid sequence of chorismate synthase from Escherichia coli K12 and its comparison with the enzyme from Neurospora crassa Biochem. J. 251 313-322 1988 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2969724&form=6&db=m 4.2.3.5 137645 The overexpression, purification and complete amino acid sequence of chorismate synthase from Escherichia coli K12 and its comparison with the enzyme from Neurospora crassa Biochem. J. 251 313-322 1988 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2969724&form=6&db=m 4.2.3.5 653910 The structure of chorismate synthase reveals a novel flavin binding site fundamental to a unique chemical reaction Structure 11 1499-1511 2003 Streptococcus pneumoniae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14656434&form=6&db=m 4.2.3.5 137665 The transient kinetics of Escherichia coli chorismate synthase: Substrate consumption, product formation, phosphate dissociation, and characterization of a flavin intermediate Biochemistry 55 9907-9916 1996 Escherichia coli -