4.1.3.16 747772 Cellular degradation of 4-hydroxy-2-oxoglutarate aldolase leads to absolute deficiency in primary hyperoxaluria type 3 FEBS Lett. 590 1467-1476 2016 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27096395&form=6&db=m 4.1.3.16 746867 Extended substrate range of thiamine diphosphate-dependent MenD enzyme by coupling of two C-C-bonding reactions Appl. Microbiol. Biotechnol. 102 8359-8372 2018 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30062480&form=6&db=m 4.1.3.16 748294 HOGA1 gene mutations of primary hyperoxaluria type 3 in tunisian patients J. Clin. Lab. Anal. 31 e22053 2017 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27561601&form=6&db=m 4.1.3.16 746641 Use of a novel microtitration protocol to obtain diffraction-quality crystals of 4-hydroxy-2-oxoglutarate aldolase from Bos taurus Acta Crystallogr. Sect. F 70 1546-1549 2014 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25372828&form=6&db=m 4.1.3.16 5238 2-keto-4-Hydroxybutyrate aldolase. Identification as 2-keto-4-hydroxyglutarate aldolase, catalytic properties, and role in mammalian metabolism of L-homoserine Biochemistry 10 1353-1364 1971 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5580656&form=6&db=m 4.1.3.16 5238 2-keto-4-Hydroxybutyrate aldolase. Identification as 2-keto-4-hydroxyglutarate aldolase, catalytic properties, and role in mammalian metabolism of L-homoserine Biochemistry 10 1353-1364 1971 Mammalia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5580656&form=6&db=m 4.1.3.16 5243 2-keto-4-Hydroxyglutarate aldolase from bovine liver Methods Enzymol. 42C 280-285 1975 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1134356&form=6&db=m 4.1.3.16 5255 2-keto-4-Hydroxyglutarate aldolase: purification of the homogeneous enzyme from bovine kidney J. Biol. Chem. 267 10507-10514 1992 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1587831&form=6&db=m 4.1.3.16 721727 4-Hydroxy-2-oxoglutarate aldolase inactivity in primary hyperoxaluria type 3 and glyoxylate reductase inhibition Biochim. Biophys. Acta 1822 1544-1552 2012 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22771891&form=6&db=m 4.1.3.16 2159 Enzymes and intermediates of hydroxyproline degradation Methods Enzymol. 17B 266-306 1971 Rattus norvegicus - 4.1.3.16 5246 Inactivation of bovine liver 2-keto-4-hydroxyglutarate aldolase by cyanide in the presence of aldehydes Biochemistry 15 2912-2917 1976 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=985699&form=6&db=m 4.1.3.16 713711 Mutations in DHDPSL are responsible for primary hyperoxaluria type III Am. J. Hum. Genet. 87 392-399 2010 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20797690&form=6&db=m 4.1.3.16 5253 Rat liver 4-hydroxy-2-ketoglutarate aldolase: purification and kinetic characterization Arch. Biochem. Biophys. 236 82-97 1985 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3966804&form=6&db=m 4.1.3.16 5250 Steady-state kinetics and inhibition studies of the aldol condensation reaction catalized by bovine liver and Escherichia coli 2-keto-4-hydroxyglutarate aldolase Biochemistry 20 2497-2502 1981 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7016177&form=6&db=m 4.1.3.16 723542 Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria PLoS ONE 6 e26021 2011 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21998747&form=6&db=m 4.1.3.16 5252 Substrates of hydroxyketoglutarate aldolase Bioorg. Chem. 12 229-234 1984 Rattus norvegicus - 4.1.3.16 5247 Sulfhydryl groups in relation to the structure and catalytic properties of 2-oxo-4-hydroxyglutarate aldolase from bovine liver Biochim. Biophys. Acta 481 212-221 1977 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=557345&form=6&db=m 4.1.3.16 728378 The enzyme 4-hydroxy-2-oxoglutarate aldolase is deficient in primary hyperoxaluria type 3 Nephrol. Dial. Transplant. 27 3191-3195 2012 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22391140&form=6&db=m 4.1.3.16 5237 The metabolism of gamma-hydroxyglutamate in rat liver. 1. Enzymic synthesis of gamma-hydroxy-alpha-ketoglutarate from pyruvate and glyoxylate Biochim. Biophys. Acta 78 617-628 1963 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14089442&form=6&db=m 4.1.3.16 5241 Variant properties of bovine liver 2-keto-4-hydroxyglutarate aldolase: its beta-decarboxylase activity, lack of substrate stereospecificity, and structural requirements for binding substrate analogs Biochim. Biophys. Acta 251 238-250 1971 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5168885&form=6&db=m