3.4.22.14 753635 Kiwifruit actinidin digests salivary amylase but not gastric lipase Food Funct. 8 3339-3345 2017 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28849829&form=6&db=m 3.4.22.14 752807 Kiwifruit cysteine protease actinidin compromises the intestinal barrier by disrupting tight junctions Biochim. Biophys. Acta 1860 516-526 2016 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26701113&form=6&db=m 3.4.22.14 753889 Physicochemical characteristics and molecular structures of gelatin extracted from bovine skin effects of actinidin and papain enzymes pretreatment Int. J. Food Prop. 22 138-153 2019 Actinidia deliciosa - 3.4.22.14 752608 Proteases, actinidin, papain and trypsin reduce oral biofilm on the tongue in elderly subjects and in vitro Arch. Oral Biol. 82 233-240 2017 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28662376&form=6&db=m 3.4.22.14 754602 Thermal inactivation of actinidin as affected by meat matrix Meat Sci. 145 238-244 2018 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29982078&form=6&db=m 3.4.22.14 733897 A kiwi juice aqueous solution as coagulant of bovine milk and its potential in Mozzarella cheese manufacture Food Bioprod. Process. 92 67-72 2014 Actinidia deliciosa - 3.4.22.14 709104 Actinidain-hydrolyzed type I collagen reveals a crucial amino acid sequence in fibril formation J. Biol. Chem. 285 17465-17470 2010 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20392700&form=6&db=m 3.4.22.14 718203 Actinidin, a protease from kiwifruit, induces changes in morphology and adhesion of T84 intestinal epithelial cells Phytochemistry 77 46-52 2012 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22257750&form=6&db=m 3.4.22.14 734567 Active actinidin retains function upon gastro-intestinal digestion and is more thermostable than the E-64-inhibited counterpart J. Sci. Food Agric. 94 3046-3052 2014 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24633720&form=6&db=m 3.4.22.14 81488 Anionic proteinase from Actinidia chinensis. Preparation and properties of the crystalline enzyme Eur. J. Biochem. 14 214-221 1970 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5506167&form=6&db=m 3.4.22.14 700289 Characterization of Bet v 1-related allergens from kiwifruit relevant for patients with combined kiwifruit and birch pollen allergy Mol. Nutr. Food Res. 52 Suppl 2 S230-S240 2008 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18925615&form=6&db=m 3.4.22.14 734050 Characterization of the allergenic potential of proteins: an assessment of the kiwifruit allergen actinidin J. Appl. Toxicol. 34 489-497 2014 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23754484&form=6&db=m 3.4.22.14 708946 Characterization of type I collagen fibril formation using thioflavin T fluorescent dye J. Biochem. 145 677-684 2009 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19204013&form=6&db=m 3.4.22.14 81477 Comparison of the refined structures of two sulphhydryl proteases: actinidin and papain Struct. Stud. Mol. Biol. Interest (Dodson, G. ; Glusker, J. P. ; Sayre, D. , eds. ) - 339-349 1981 Actinidia chinensis - 3.4.22.14 708861 Component-resolved diagnosis of kiwifruit allergy with purified natural and recombinant kiwifruit allergens J. Allergy Clin. Immunol. 125; 687-94 694.e1 2010 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20061012&form=6&db=m 3.4.22.14 733394 Conformational mobility of active and E-64-inhibited actinidin Biochim. Biophys. Acta 1830 4790-4799 2013 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23803410&form=6&db=m 3.4.22.14 81493 Crystal structure of an actinidin-E-64 complex Biochemistry 31 5172-5176 1992 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1606141&form=6&db=m 3.4.22.14 81491 Detection of a free enzyme isomerisation in actinidin catalysed hydrolysis Biochem. Soc. Trans. 26 S173 1998 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9649848&form=6&db=m 3.4.22.14 81475 Differences in the chemical and catalytic characteristics of two crystallographically identical enzyme catalytic sites. Characterization of actinidin and papain by a combination of pH-dependent substrate catalysis kinetics and reactivity probe studies tar Biochem. J. 247 181-193 1987 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2825655&form=6&db=m 3.4.22.14 81478 Differences in the interaction of the catalytic groups of the active centres of actinidin and papain. Rapid purification of fully active actinidin by covalent chromatography and characterization of its active centre by use of two-protonic-state reactivity probes Biochem. J. 197 739-746 1981 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7034724&form=6&db=m 3.4.22.14 709327 Effect of actinidin on the protein solubility, water holding capacity, texture, electrophoretic pattern of beef, and on the quality attributes of a sausage product J. Food Sci. 74 C221-C226 2009 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19397706&form=6&db=m 3.4.22.14 700290 Effects of gastrointestinal digestion and heating on the allergenicity of the kiwi allergens Act d 1, actinidin, and Act d 2, a thaumatin-like protein Mol. Nutr. Food Res. 52 1130-1139 2008 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18655003&form=6&db=m 3.4.22.14 669155 Effects of high concentration of salts on the esterase activity and structure of a kiwifruit peptidase, actinidain J. Biochem. 139 1065-1071 2006 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16788057&form=6&db=m 3.4.22.14 717622 Evaluation of IgE reactivity of active and thermally inactivated actinidin, a biomarker of kiwifruit allergy Food Chem. Toxicol. 50 1013-1018 2012 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22227218&form=6&db=m 3.4.22.14 81489 Hybrids of chicken cystatin with human kininogen domain 2 sequences exhibit novel inhibition of calpain, improved inhibition of actinidin and impaired inhibition of papain, cathepsin L and cathepsin B Eur. J. Biochem. 235 534-542 1996 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8654398&form=6&db=m 3.4.22.14 686912 Identification and characterisation of acidic and novel basic forms of actinidin, the highly abundant cysteine protease from kiwifruit Funct. Plant Biol. 34 946-961 2007 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32689423&form=6&db=m 3.4.22.14 686912 Identification and characterisation of acidic and novel basic forms of actinidin, the highly abundant cysteine protease from kiwifruit Funct. Plant Biol. 34 946-961 2007 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32689423&form=6&db=m 3.4.22.14 81494 Identification of actinidin as the major allergen of kiwi fruit J. Allergy Clin. Immunol. 101 531-537 1998 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9564807&form=6&db=m 3.4.22.14 697404 Immunoglobulin E recognition patterns to purified Kiwifruit (Actinidinia deliciosa) allergens in patients sensitized to Kiwi with different clinical symptoms Clin. Exp. Allergy 38 1220-1228 2008 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18205857&form=6&db=m 3.4.22.14 733988 Improving the activity and stability of actinidin by immobilization on gold nanorods Int. J. Biol. Macromol. 72 1176-1181 2015 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25450831&form=6&db=m 3.4.22.14 689327 In vitro and in vivo anthelmintic efficacy of plant cysteine proteinases against the rodent gastrointestinal nematode, Trichuris muris Parasitology 132 681-689 2006 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16448585&form=6&db=m 3.4.22.14 81490 Interaction of recombinant human cystatin C with the cysteine proteinases papain and actinidin Biochem. J. 281 49-55 1992 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1731767&form=6&db=m 3.4.22.14 686853 Isolation of cysteine protease actinidin gene from Chinese wild kiwifruit and its expression in Escherichia coli Food Sci. Biotechnol. 16 294-298 2007 Actinidia chinensis - 3.4.22.14 667472 Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation Biochem. J. 378 699-703 2004 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14640975&form=6&db=m 3.4.22.14 81487 Kinetic studies on the thiol protease from Actinidia chinensis FEBS Lett. 27 282-284 1972 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4664227&form=6&db=m 3.4.22.14 698404 Kiwellin, a modular protein from green and gold kiwi fruits: evidence of in vivo and in vitro processing and IgE binding J. Agric. Food Chem. 56 3812-3817 2008 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18442249&form=6&db=m 3.4.22.14 684521 Kiwifruit actinidin: a proper new collagenase for isolation of cells from different tissues Appl. Biochem. Biotechnol. 144 123-131 2008 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18456944&form=6&db=m 3.4.22.14 686172 Kiwifruit allergy: actinidin is not a major allergen in the United Kingdom Clin. Exp. Allergy 37 1340-1348 2007 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17845415&form=6&db=m 3.4.22.14 718236 Mapping, complementation, and targets of the cysteine protease actinidin in kiwifruit Plant Physiol. 158 376-388 2012 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22039217&form=6&db=m 3.4.22.14 718236 Mapping, complementation, and targets of the cysteine protease actinidin in kiwifruit Plant Physiol. 158 376-388 2012 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22039217&form=6&db=m 3.4.22.14 81476 Photochemical oxidation of actinidin, a thiol protease from Actinidia chinensis Experientia 43 318-319 1987 Actinidia chinensis - 3.4.22.14 81486 Preliminary crystallographic data for actinidin, a thiol protease from Actinidia chinensis J. Mol. Biol. 74 411-412 1973 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4692857&form=6&db=m 3.4.22.14 650650 Preparation and structural analysis of actinidain-processed atelocollagen of yellowfin tuna (Thunnus albacares) Biosci. Biotechnol. Biochem. 68 861-867 2004 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15118315&form=6&db=m 3.4.22.14 733137 Proteolytic activities of kiwifruit actinidin (Actinidia deliciosa cv. Hayward) on different fibrous and globular proteins: a comparative study of actinidin with papain Appl. Biochem. Biotechnol. 172 4025-4037 2014 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24604128&form=6&db=m 3.4.22.14 733137 Proteolytic activities of kiwifruit actinidin (Actinidia deliciosa cv. Hayward) on different fibrous and globular proteins: a comparative study of actinidin with papain Appl. Biochem. Biotechnol. 172 4025-4037 2014 Actinidia deliciosa cv. Hayward http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24604128&form=6&db=m 3.4.22.14 81474 Purification and characterization of six kiwifruit proteases isolated with two ion-exchange resins, Toyopearl-Super Q and Bakerbond WP-PEI Biosci. Biotechnol. Biochem. 60 1994-2000 1996 Actinidia chinensis - 3.4.22.14 81492 Purification and circular dichroism studies of multiple forms of actinidin from Actinidia chinensis (kiwifruit) Plant Sci. 106 227-232 1995 Actinidia chinensis - 3.4.22.14 717024 Structural analysis of actinidin and a comparison of cadmium and sulfur anomalous signals from actinidin crystals measured using in-house copper- and chromium-anode X-ray sources Acta Crystallogr. Sect. D 66 1323-1333 2010 Actinidia arguta http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21123873&form=6&db=m 3.4.22.14 81480 Structure of actinidin after refinement at 1.7 A resolution J. Mol. Biol. 141 441-484 1980 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7003158&form=6&db=m 3.4.22.14 81484 Structure of actinidin: details of the polypeptide chain conformation and active site from an electron density map at 2-8 A resolution J. Mol. Biol. 115 263-277 1977 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=592367&form=6&db=m 3.4.22.14 667529 Temperature-dependences of the kinetics of reactions of papain and actinidin with a series of reactivity probes differing in key molecular recognition features Biochem. J. 396 17-21 2006 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16445383&form=6&db=m 3.4.22.14 81482 The actinidin-catalysed hydrolysis of N-a-benzyloxycarbonyl-L-lysine p-nitrophenyl ester. pH dependence and mechanism Eur. J. Biochem. 36 575-582 1973 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4730966&form=6&db=m 3.4.22.14 81483 The action of proteinase A 2 of Actinidia chinensis on the B-chain of oxidized insulin Biochim. Biophys. Acta 293 226-231 1973 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4734375&form=6&db=m 3.4.22.14 81481 The amino acid sequence of the tryptic peptides from actinidin, a proteolytic enzyme from the fruit of Actinidia chinensis Biochem. J. 173 73-83 1978 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=687380&form=6&db=m 3.4.22.14 733900 The effect of kiwifruit (Actinidia deliciosa) cysteine protease actinidin on the occludin tight junction network in T84 intestinal epithelial cells Food Chem. Toxicol. 72 61-68 2014 Actinidia deliciosa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25042511&form=6&db=m 3.4.22.14 81473 The interplay of electrostatic and binding interactions determining active centre chemistry and catalytic activity in actinidin and papain [letter Biochem. J. 257 309-310 1989 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2920023&form=6&db=m 3.4.22.14 81479 The specificity of actinidin and its relationship to the structure of the enzyme Biochim. Biophys. Acta 616 30-34 1980 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7002215&form=6&db=m 3.4.22.14 81485 The structure of actinidin at 5-5 A resolution J. Mol. Biol. 101 185-196 1976 Actinidia chinensis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1263257&form=6&db=m