1.11.1.27 755233 Activation of the antioxidant enzyme 1-CYS peroxiredoxin requires glutathionylation mediated by heterodimerization with pi GST Proc. Natl. Acad. Sci. USA 101 3780-3785 2004 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15004285&form=6&db=m 1.11.1.27 754106 Characterization of the Vibrio vulnificus 1-Cys peroxiredoxin Prx3 and regulation of its expression by the Fe-S cluster regulator IscR in response to oxidative stress and iron starvation J. Biol. Chem. 289 36263-36274 2014 Vibrio vulnificus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25398878&form=6&db=m 1.11.1.27 754106 Characterization of the Vibrio vulnificus 1-Cys peroxiredoxin Prx3 and regulation of its expression by the Fe-S cluster regulator IscR in response to oxidative stress and iron starvation J. Biol. Chem. 289 36263-36274 2014 Vibrio vulnificus MO6-24/O http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25398878&form=6&db=m 1.11.1.27 757519 Construction and activity analyses of single functional mouse peroxiredoxin 6 (Prdx6) J. Vet. Res. 63 99-105 2019 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30989141&form=6&db=m 1.11.1.27 755815 Hyperoxidation of peroxiredoxin 6 induces alteration from dimeric to oligomeric state Antioxidants (Basel) 8 33 2019 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30717364&form=6&db=m 1.11.1.27 765749 Identification of peroxiredoxin 6 as a direct target of withangulatin A by quantitative chemical proteomics in non-small cell lung cancer Redox Biol. 46 102130 2021 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34517184&form=6&db=m 1.11.1.27 763922 Peroxiredoxin 6 down-regulation induces metabolic remodeling and cell cycle arrest in HepG2 cells Antioxidants (Basel) 8 505 2019 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31652719&form=6&db=m 1.11.1.27 755892 Peroxiredoxin 6 in the repair of peroxidized cell membranes and cell signaling Arch. Biochem. Biophys. 617 68-83 2017 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27932289&form=6&db=m 1.11.1.27 755813 Peroxiredoxin 6 inhibits osteogenic differentiation and bone formation through human dental pulp stem cells and induces delayed bone development Antioxid. Redox Signal. 30 1969-1982 2019 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29792351&form=6&db=m 1.11.1.27 765401 Peroxiredoxin 6 mediates protective function of astrocytes in Abeta proteostasis Mol. Neurodegener. 15 50 2020 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32907613&form=6&db=m 1.11.1.27 765792 pH induced conformational alteration in human peroxiredoxin 6 might be responsible for its resistance against lysosomal pH or high temperature Sci. Rep. 11 9657 2021 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33958651&form=6&db=m 1.11.1.27 754068 Purification and characterization of a chimeric enzyme from Haemophilus influenzae Rd that exhibits glutathione-dependent peroxidase activity J. Biol. Chem. 278 16658-16666 2003 Haemophilus influenzae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12606554&form=6&db=m 1.11.1.27 754068 Purification and characterization of a chimeric enzyme from Haemophilus influenzae Rd that exhibits glutathione-dependent peroxidase activity J. Biol. Chem. 278 16658-16666 2003 Haemophilus influenzae ATCC 51907 http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12606554&form=6&db=m 1.11.1.27 765775 Structural basis of peroxidase catalytic cycle of human Prdx6 Sci. Rep. 10 17416 2020 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33060708&form=6&db=m 1.11.1.27 755814 The role of peroxiredoxin 6 in cell signaling Antioxidants (Basel) 7 172 2018 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30477202&form=6&db=m 1.11.1.27 755814 The role of peroxiredoxin 6 in cell signaling Antioxidants (Basel) 7 172 2018 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30477202&form=6&db=m 1.11.1.27 675868 2-Cys Peroxiredoxin TPx-1 is involved in gametocyte development in Plasmodium berghei Mol. Biochem. Parasitol. 148 44-51 2006 Plasmodium berghei http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16597467&form=6&db=m 1.11.1.27 700171 Antioxidant activity of the yeast mitochondrial one-Cys peroxiredoxin is dependent on thioredoxin reductase and glutathione in vivo Mol. Cell. Biol. 29 3229-3240 2009 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19332553&form=6&db=m 1.11.1.27 695877 Binding of peroxiredoxin 6 to substrate determines differential phospholipid hydroperoxide peroxidase and phospholipase A(2) activities Arch. Biochem. Biophys. 485 139-149 2009 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19236840&form=6&db=m 1.11.1.27 655970 Characterization of a mammalian peroxiredoxin that contains one conserved cysteine J. Biol. Chem. 273 6303-6311 1998 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9497358&form=6&db=m 1.11.1.27 671740 Engineering functional artificial hybrid proteins between poplar peroxiredoxin II and glutaredoxin or thioredoxin Biochem. Biophys. Res. Commun. 341 1300-1308 2006 Populus tremula x Populus tremuloides http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16476584&form=6&db=m 1.11.1.27 697308 In vitro and in silico characterization of peroxiredoxin 6 modified by 4-hydroxynonenal and 4-oxononenal Chem. Res. Toxicol. 21 2289-2299 2008 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19548352&form=6&db=m 1.11.1.27 655577 Molecular and catalytic properties of a peroxiredoxin-glutaredoxin hybrid from Neisseria meningitidis FEBS Lett. 554 149-153 2003 Neisseria meningitidis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14596930&form=6&db=m 1.11.1.27 673786 Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism Free Radic. Biol. Med. 38 1422-1432 2005 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15890616&form=6&db=m 1.11.1.27 673786 Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism Free Radic. Biol. Med. 38 1422-1432 2005 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15890616&form=6&db=m 1.11.1.27 673786 Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism Free Radic. Biol. Med. 38 1422-1432 2005 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15890616&form=6&db=m 1.11.1.27 673786 Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism Free Radic. Biol. Med. 38 1422-1432 2005 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15890616&form=6&db=m 1.11.1.27 673786 Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism Free Radic. Biol. Med. 38 1422-1432 2005 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15890616&form=6&db=m 1.11.1.27 710899 Peroxiredoxin 6: A bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities Antioxid. Redox Signal. 15 831-844 2010 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20919932&form=6&db=m 1.11.1.27 710899 Peroxiredoxin 6: A bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities Antioxid. Redox Signal. 15 831-844 2010 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20919932&form=6&db=m 1.11.1.27 710899 Peroxiredoxin 6: A bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities Antioxid. Redox Signal. 15 831-844 2010 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20919932&form=6&db=m 1.11.1.27 710899 Peroxiredoxin 6: A bifunctional enzyme with glutathione peroxidase and phospholipase A2 activities Antioxid. Redox Signal. 15 831-844 2010 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20919932&form=6&db=m 1.11.1.27 654776 Recombinant human peroxiredoxin VI: preparation and protective properties in vitro Biochemistry 67 1235-1239 2002 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12495419&form=6&db=m 1.11.1.27 673521 Roles of 1-Cys peroxiredoxin in haem detoxification in the human malaria parasite Plasmodium falciparum FEBS J. 272 1784-1791 2005 Plasmodium falciparum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15794764&form=6&db=m