3.6.1.29 P1,P3-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP - - 3.6.1.29 P1,P3-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP the dimeric enzyme contains a catalytic histidine triad with H96 forming a covalent intermediate at the alpha-phosphate of P1,P3-bis(5'-adenosyl)triphosphate, S128, H96 and H98 are essential for the reaction, structure overview 667667 3.6.1.29 P1,P3-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP two-step reaction mechanism via a fragile histidine triad Fhit-AMP intermediate and release of MgADP-, kinetic of the reaction steps, overview 667612