2.5.1.90 (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate isopentenyl diphosphate condensation rather than product release is rate limiting 707542 2.5.1.90 (2E,6E)-farnesyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-octaprenyl diphosphate sequential mechanism 707356